SCHEMBL7030841

SCHEMBL7030841

CC=CC(=O)OCC(O)COCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.37
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.33
TSHR P16473 4/20 0.33
GSTP1 P09211 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5535259 0.91 TSHR (0.35) HCAR2MAPTATMTSHRGSTP1
SCHEMBL347488 0.91 TSHR (0.35) HCAR2MAPTATMTSHRGSTP1
SCHEMBL20335453 0.89 TSHR (0.39) HCAR2MAPTATMTSHRGSTP1
SCHEMBL28138681 0.88 HSD17B10 (0.42) HCAR2MAPTATMMEN1KMT2A
SCHEMBL144845 0.87 HCAR2 (0.36) HCAR2MAPTATMTSHRGSTP1
SCHEMBL21081997 0.86 HCAR2 (0.35) HCAR2ATMTSHRGSTP1MEN1
SCHEMBL21081994 0.86 HCAR2 (0.35) HCAR2ATMTSHRGSTP1MEN1
SCHEMBL26109047 0.86 HCAR2 (0.35) HCAR2ATMTSHRGSTP1MEN1
SCHEMBL14874676 0.84 TSHR (0.35) HCAR2MAPTTSHRGSTP1ALDH1A1
SCHEMBL996290 0.84 LPAR5 (0.37) HCAR2MAPTATMTSHRGSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112752776-B Resin composition for photofabrication 可乐丽则武齿科株式会社 2024-02-09 CN disclosed
CN-116367806-A Curable composition for dentistry having excellent color tone adaptability 可乐丽则武齿科株式会社 2023-06-30 CN disclosed
CN-113226247-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2021-08-06 CN disclosed
WO-2021125246-A1 FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF クラレノリタケデンタル株式会社 2021-06-24 WO disclosed
CN-112752776-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2021-05-04 CN disclosed
CN-108366910-B Dental adhesive kit 可乐丽则武齿科株式会社 2021-04-27 CN disclosed
WO-2021054457-A1 CURABLE COMPOSITION FOR DENTISTRY クラレノリタケデンタル株式会社 2021-03-25 WO disclosed
CN-109641432-B Antifogging laminate 三井化学株式会社 2021-03-09 CN disclosed
CN-106714766-B Method for producing a particulate dental filler composition 登特斯普伊德特雷有限公司 2020-11-24 CN disclosed
CN-107003779-B Image display device with touch panel 三菱化学株式会社 2020-05-26 CN disclosed
CN-101163766-B Adhesive composition KURARAY MEDICAL INC 2011-05-04 CN disclosed
CN-101835925-A Stamp and method for producing same, method for producing molded body, and aluminum master mold for stamp MITSUBISHI RAYON CO 2010-09-15 CN disclosed
CN-101484614-A Mold, method for manufacturing mold, and method for manufacturing sheet MITSUBISHI RAYON CO (JP) 2009-07-15 CN disclosed
CN-101163766-A Adhesive composition KURARAY MEDICAL INC (JP) 2008-04-16 CN disclosed
CN-101001886-A Redox curing-type nonaqueous curable composition KURARAY MEDICAL INC (JP) 2007-07-18 CN disclosed
US-20030175659-A1 Multifunctional dentin bonding agent BISCO, INC. 2003-09-18 US disclosed
US-20030064102-A1 Antimicrobial Composition NAKATSUKA KAZUMITSU (JP) 2003-04-03 US disclosed
EP-0821931-B1 Metal fluoride particles and a dental composition including said metal fluoride particles KURARAY CO (JP) 2003-01-15 EP disclosed
US-5908879-A A POLYSILOXANE COATING ON THE SURFACE OF THE PARTICLE. KURARAY CO., LTD. (JP) 1999-06-01 US disclosed
EP-0821931-A2 Metal fluoride particles and a dental composition including said metal fluoride particles KURARAY CO., LTD. (JP) 1998-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030175659-A1 Multifunctional dentin bonding agent C9, MACF1, GGH HCAR2 240/4885MAPT 2751/4885ATM 4710/4885
US-20030064102-A1 Antimicrobial Composition AAAS, H1-0, H1-10 HCAR2 2717/4885MAPT 880/4885ATM 3545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.