SCHEMBL6516855

SCHEMBL6516855

C[Si](C)(C)C#Cc1cccc(C#C[Si](C)(C)C)c1C=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 1/20 0.39
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22721439 0.88 ALDH1A1 (0.52) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL3056776 0.88 CREBBP (0.35) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL31562390 0.88 CREBBP (0.35) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL31562726 0.85 KDM4E (0.35) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL3059913 0.80 MAOB (0.34) CREBBP
SCHEMBL31562595 0.79 CREBBP (0.33) CREBBP
SCHEMBL709085 0.78 KMT2A (0.44) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL24216938 0.77 CREBBP (0.35) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL28422107 0.77 ERN1 (0.37) CREBBPALDH1A1MEN1KMT2AKDM4E
SCHEMBL30408149 0.77 CREBBP (0.35) CREBBPALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916982-B2 Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays NORTH CAROLINA STATE UNIVERSITY (US) 2005-07-12 US disclosed
WO-2003105237-A1 SYNTHESIS OF PERYLENE-PORPHYRIN BUILDING BLOCKS AND POLYMERS THEREOF FOR THE PRODUCTION OF LIGHT-HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2003-12-18 WO disclosed
US-20030075216-A1 Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-04-24 US disclosed