Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139993 | 0.90 | MAPT (0.54) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL15655813 | 0.89 | PPARG (0.51) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL19833118 | 0.87 | PPARG (0.47) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL18130572 | 0.87 | PPARG (0.47) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL23728187 | 0.86 | PPARG (0.45) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL665809 | 0.86 | CYP26A1 (0.49) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL6675275 | 0.86 | ALDH1A1 (0.54) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL5997313 | 0.86 | PPARG (0.50) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL25385559 | 0.86 | PPARG (0.50) | PPARGPPARAALDH1A1KDM4EMAPT | |
| SCHEMBL28679766 | 0.85 | PPARG (0.49) | PPARGPPARAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953798-B1 | β-alanine derivates | CELLTECH R&D LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |