Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 6/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 6/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 5/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10176532 | 0.91 | PTPN7 (0.44) | PTPN7PTPN12PTPN22POLBMEN1 | |
| SCHEMBL703259 | 0.89 | MEN1 (0.38) | PTPN7PTPN12PTPN22POLBMEN1 | |
| SCHEMBL651308 | 0.85 | ABL1 (0.43) | POLBMEN1KMT2APTPN11HSD11B1 | |
| SCHEMBL650135 | 0.85 | ABL1 (0.43) | POLBMEN1KMT2APTPN11HSD11B1 | |
| SCHEMBL10176547 | 0.84 | MAPT (0.47) | POLBMEN1KMT2APTPN11L3MBTL1 | |
| SCHEMBL649107 | 0.83 | MEN1 (0.44) | POLBMEN1KMT2APTPN11L3MBTL1 | |
| SCHEMBL652202 | 0.83 | MEN1 (0.44) | POLBMEN1KMT2APTPN11L3MBTL1 | |
| SCHEMBL650770 | 0.83 | MAPT (0.41) | PTPN7PTPN12PTPN22POLBDUSP3 | |
| SCHEMBL10176528 | 0.83 | MAPT (0.42) | PTPN7PTPN12PTPN22POLBDUSP3 | |
| SCHEMBL699657 | 0.83 | MAPT (0.41) | PTPN7PTPN12PTPN22POLBDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | PTPN7 437/4885PTPN12 1722/4885PTPN22 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.