SCHEMBL6517433

SCHEMBL6517433

CC1CCCC(OC=O)(C(=O)OC2CCCCC2)C1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CHRM3 P20309 1/20 0.36
CYP2C19 P33261 1/20 0.36
EPHX1 P07099 2/20 0.34
NAAA Q02083 1/20 0.32
CYP19A1 P11511 3/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5224647 0.77 CYP2C19 (0.40) CHRM3CYP2C19EPHX1CYP19A1
SCHEMBL16234619 0.69 CYP3A4 (0.42) CHRM3MAPT
SCHEMBL16086282 0.66 CYP2C19 (0.48) CHRM3CYP2C19EPHX1NAAACYP19A1
SCHEMBL27660738 0.65 CYP2C19 (0.49) CHRM3CYP2C19EPHX1NAAACYP19A1
SCHEMBL9485096 0.64 CYP2C19 (0.52) CHRM3CYP2C19EPHX1NAAACYP19A1
SCHEMBL16086274 0.64 CYP2C19 (0.47) CHRM3CYP2C19EPHX1NAAACYP19A1
SCHEMBL28778803 0.64 CYP2C19 (0.52) CHRM3CYP2C19EPHX1NAAACYP19A1
SCHEMBL5493739 0.64 CYP2C19 (0.52) CHRM3CYP2C19EPHX1NAAACYP19A1
SCHEMBL28983033 0.64 CYP1A2 (0.44) CYP1A2MAPT
SCHEMBL27873180 0.64 CYP1A2 (0.34) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050272132-A1 Production of polyketides and other natural products BIOTICA TECHNOLOGY LIMITED (GB) 2005-12-08 US disclosed