Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234619 | 0.78 | CYP3A4 (0.42) | CHRM3 | |
| SCHEMBL6517433 | 0.77 | CYP1A2 (0.36) | CYP2C19CHRM3EPHX1CYP19A1 | |
| SCHEMBL1352343 | 0.74 | — | — | |
| SCHEMBL6623048 | 0.73 | CYP2C19 (0.40) | CYP2C19CHRM3EPHX1TPSAB1TPSD1 | |
| SCHEMBL383269 | 0.73 | AKR1C1 (0.34) | CYP2C19 | |
| SCHEMBL7435411 | 0.72 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL383939 | 0.71 | CYP2C19 (0.35) | CYP2C19 | |
| SCHEMBL6291533 | 0.71 | NPSR1 (0.38) | — | |
| SCHEMBL11699430 | 0.70 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL9485096 | 0.69 | CYP2C19 (0.52) | CYP2C19CHRM3MMP1MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-B1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK AS (DK) | 2007-09-05 | — | — | EP | disclosed |