Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190659 | 0.86 | KDM4E (0.38) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL353086 | 0.84 | GLA (0.42) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL7644644 | 0.81 | MCL1 (0.38) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL2246620 | 0.80 | HDAC3 (0.47) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL10901492 | 0.80 | KDM4E (0.34) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL1690910 | 0.80 | GLA (0.45) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL11031369 | 0.78 | KDM4E (0.35) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL9861601 | 0.77 | KDM4E (0.37) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Acrylonitrile SCHEMBL9249177 | 0.77 | GLA (0.38) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL8972957 | 0.77 | GLA (0.36) | LMNAMAPTALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6863871-B2 | Sealing closure for high pressure vessels in microwave assisted chemistry | CEM CORPORATION (US) | 2005-03-08 | — | — | US | claimed |
| EP-1181093-B1 | SEALING CLOSURE FOR HIGH PRESSURE VESSELS IN MICROWAVE ASSISTED CHEMISTRY | CEM CORP (US) | 2003-07-16 | — | — | EP | claimed |
| EP-1181093-A1 | SEALING CLOSURE FOR HIGH PRESSURE VESSELS IN MICROWAVE ASSISTED CHEMISTRY | CEM Corporation (US) | 2002-02-27 | — | — | EP | claimed |
| US-20010022949-A1 | Sealing closure for high pressure vessels in microwave assisted chemistry | HARGETT WYATT PRICE (US) | 2001-09-20 | — | — | US | claimed |
| US-6287526-B1 | Sealing closure for high pressure vessels in microwave assisted chemistry | CEM CORPORATION | 2001-09-11 | — | — | US | claimed |
| WO-2000072957-A1 | SEALING CLOSURE FOR HIGH PRESSURE VESSELS IN MICROWAVE ASSISTED CHEMISTRY | CEM CORPORATION (US) | 2000-12-07 | — | — | WO | claimed |