SCHEMBL353086

SCHEMBL353086

C=CC=CC(C=Cc1ccccc1)=C(C)C#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 2/20 0.37
MCL1 Q07820 1/20 0.37
LMNA P02545 5/20 0.37
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
PLIN1 O60240 2/20 0.37
RECQL P46063 2/20 0.37
PLIN5 Q00G26 2/20 0.37
ABHD5 Q8WTS1 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TNKS O95271 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1404410 0.89 GLA (0.52) GLATDP1ALOX15KDM4EMCL1
SCHEMBL6518213 0.84 LMNA (0.39) GLATDP1ALOX15KDM4EMCL1
SCHEMBL9190659 0.83 KDM4E (0.38) GLATDP1ALOX15KDM4EMCL1
SCHEMBL1690910 0.83 GLA (0.45) GLATDP1ALOX15KDM4EMCL1
Acrylonitrile SCHEMBL9249177 0.80 GLA (0.38) GLATDP1ALOX15KDM4EMCL1
SCHEMBL8972957 0.80 GLA (0.36) GLATDP1ALOX15KDM4EMCL1
Acrylonitrile SCHEMBL22656767 0.79 GLA (0.44) GLATDP1ALOX15MCL1LMNA
SCHEMBL11126989 0.79 GLA (0.41) GLATDP1KDM4EMCL1LMNA
SCHEMBL4878883 0.79 TDP1 (0.41) GLATDP1KDM4EMCL1LMNA
SCHEMBL6053030 0.79 GLA (0.42) GLATDP1ALOX15KDM4EMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024078801-A1 CURABLE AND ELECTRICALLY DEBONDABLE ONE-COMPONENT (1K) STRUCTURAL ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2024-04-18 WO claimed
EP-4353760-A1 CURABLE AND ELECTRICALLY DEBONDABLE ONE-COMPONENT (1K) STRUCTURAL ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2024-04-17 EP claimed
EP-2379620-B1 POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-05-30 EP claimed
CN-102272194-A Polycarbonate compositions 2011-12-07 CN claimed
EP-2379620-A1 POLYCARBONATE COMPOSITIONS SABIC Innovative Plastics IP B.V. (NL) 2011-10-26 EP claimed
US-7999037-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-08-16 US claimed
WO-2010076680-A1 POLYCARBONATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-07-08 WO claimed
US-20100168311-A1 POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2010-07-01 US claimed
WO-2009029412-A1 DOOR MODULE WITH INTEGRATED CABLE BUNDLE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-03-05 WO claimed
US-20090056230-A1 Door Module With Integrated cable bundle EXXONMOBIL CHEMICAL PATENTS INC. 2009-03-05 US claimed
WO-2007111782-A1 DOOR ASSEMBLY WITH CORE MODULE HAVING INTEGRATED BELT LINE REINFORCEMENT EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-04 WO claimed
WO-2007111878-A2 DOOR ASSEMBLY WITH INTEGRATED WINDOW SEALING SYSTEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-04 WO claimed
WO-2007111785-A1 CORE MODULE FOR DOOR ASSEMBLY HAVING INTEGRATED REINFORCEMENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-04 WO claimed
US-20070220811-A1 Door assembly with integrated window sealing system EXXONMOBIL CHEMICAL PATENTS INC. 2007-09-27 US claimed
US-20070222257-A1 Core module for door assembly having integrated reinforcements EXXONMOBIL CHEMICAL PATENTS INC. 2007-09-27 US claimed
EP-0579576-B1 2,4-Dialkyl-6-sec-alkylphenols CIBA GEIGY AG (CH) 1998-05-20 EP claimed
US-4992504-A Heat resistance, photostability CIBA-GEIGY CORPORATION (US) 1991-02-12 US claimed
US-4354007-A Process for preparing oxidatively-stable polymers SCOTT GERALD 1982-10-12 US claimed
US-3965230-A Process of manufacturing lacquered articles of cold rolled abs resin MONSANTO COMPANY (US) 1976-06-22 US claimed
US-3956569-A IMPROVES ADHESION AND HYDOPHILIC PROPERTIES NIPPON ZEON CO., LTD. (JA) 1976-05-11 US claimed