SCHEMBL651905

SCHEMBL651905

O=C1C=CCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541182 0.93
SCHEMBL541181 0.93
SCHEMBL30545269 0.91 ALDH1A1 (0.39)
SCHEMBL4954670 0.91 ALDH1A1 (0.39)
SCHEMBL4954673 0.91 ALDH1A1 (0.39)
SCHEMBL4954677 0.91 ALDH1A1 (0.39)
SCHEMBL29636334 0.91 ALDH1A1 (0.39)
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL49488 0.84
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL31482438 0.82
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL9464948 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109665980-B Refining method of caprolactam 中国石油化工股份有限公司 2021-01-08 CN claimed
CN-109665997-B Preparation method of caprolactam 中国石油化工股份有限公司 2021-01-08 CN claimed
CN-109665998-B Method and apparatus for refining caprolactam 中国石油化工股份有限公司 2021-01-08 CN claimed
US-20150045496-A1 THERMO-REVERSIBLE POLYBUTADIENE RUBBER BLEND WITH SELF-HEALING NATURE RELIANCE INDUSTRIES LIMITED (IN) 2015-02-12 US claimed
WO-2013164843-A1 THERMO-REVERSIBLE POLYBUTADIENE RUBBER BLEND WITH SELF-HEALING NATURE RELIANCE INDUSTRIES LTD. (IN) 2013-11-07 WO claimed
US-20110183386-A1 PREPARATION OF EPSILON-CAPROLACTAM FROM (Z)-6,7-DIHYDRO-1H-AZEPIN-2(5H)-ONE DSM IP ASSETS B.V. (NL) 2011-07-28 US claimed
US-20110136186-A1 PREPARATION OF ALPHA-AMINO-EPSILON-CAPROLACTAM VIA LYSINE CYCLISATION DSM IP ASSETS B.V. (NL) 2011-06-09 US claimed
EP-2291531-A1 PREPARATION OF EPSILON-CAPROLACTAM FROM (Z)-6,7-DIHYDRO-1H-AZEPIN-2(5H)-ONE DSM IP Assets B.V. (NL) 2011-03-09 EP claimed
WO-2009142490-A1 PREPARATION OF EPSILON-CAPROLACTAM FROM (Z)-6,7-DIHYDRO-1H-AZEPIN-2(5H)-ONE DSM IP ASSETS B.V. (NL) 2009-11-26 WO claimed
EP-2123767-A1 Preparation of epsilon-caprolactam via lysine cyclisation DSM IP Assets B.V. (NL) 2009-11-25 EP claimed
EP-2123768-A1 Preparation of (Z)-6,7-dihydro-1H-azepin-2(5H)-one DSM IP Assets B.V. (NL) 2009-11-25 EP claimed
EP-1572772-B1 METHOD FOR PRODUCING POLYURETHANE PREPOLYMERS IN THE PRESENCE OF A CATALYST HENKEL KGAA (DE) 2006-09-06 EP claimed
US-20060004175-A1 Method for producing a polyurethane prepolymer HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-01-05 US claimed
US-6433166-B1 None US disclosed
CN-118697737-A Application of piperlonguminine analogue compound in preparation of medicines for treating cervical cancer and/or liver cancer 赣南医学院第一附属医院 2024-09-27 CN disclosed
CN-114907263-B Process for refining caprolactam 中国石油化工股份有限公司 2024-07-09 CN disclosed
EP-0267277-A4 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS. NELSON RES & DEV COMPANY (US) 1990-03-21 EP disclosed
US-4755535-A Compositions comprising 1-substituted azacycloalkenes NELSON RESEARCH & DEVELOPMENT CO. (US) 1988-07-05 US disclosed
EP-0267277-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS. NELSON RES & DEV (US) 1988-05-18 EP disclosed
WO-1987006583-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS NELSON RESEARCH AND DEVELOPMENT COMPANY (US) 1987-11-05 WO disclosed