SCHEMBL65195

SCHEMBL65195

c1cnc2cccn2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27769891 0.97
Pyrazine SCHEMBL28188517 0.93 DYRK1A (0.41)
SCHEMBL7883 0.82
SCHEMBL268000 0.82
SCHEMBL19463910 0.80 ADORA3 (0.45)
SCHEMBL31249062 0.80 ADORA3 (0.45)
Hydrochloric Acid SCHEMBL18952247 0.80 ADORA3 (0.45)
Hydrochloric Acid SCHEMBL30557265 0.80 ADORA3 (0.45)
SCHEMBL30084676 0.80 ADORA3 (0.45)
Water SCHEMBL6703860 0.80 ADORA3 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658655-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP claimed
US-20250353858-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-20 US claimed
EP-4646271-A1 SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES Mirati Therapeutics, Inc. (US) 2025-11-12 EP claimed
EP-4620470-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-24 EP claimed
EP-4615455-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-17 EP claimed
US-20250059164-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-20 US claimed
WO-2024264017-A2 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-12-26 WO claimed
WO-2024160278-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO claimed
WO-2024148150-A1 SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES Mirati Therapeutics, Inc. (US) 2024-07-11 WO claimed
EP-3724191-A1 5-(2-(2,5-DIFLUOROPHENYL)PYRROLIDIN-1 -YL)-3-(1H-PYRAZOL-1-YL)PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS AS TRK KINASE INHIBITORS FOR TREATING CANCER Pyramid Biosciences, Inc. (US) 2020-10-21 EP claimed
US-20140072485-A1 METHODS FOR SEPARATING MEDICAL ISOTOPES USING IONIC LIQUIDS UT-BATTELLE, LLC (US) 2014-03-13 US claimed
US-20130280151-A1 IONIC LIQUID-FUNCTIONALIZED MESOPOROUS SORBENTS AND THEIR USE IN THE CAPTURE OF POLLUTING GASES U.S. DEPARTMENT OF ENERGY 2013-10-24 US claimed
CN-101648953-B Imidazo (1,2-b) pyrrolo (1,2-f) pyridazine derivative as well as preparation method and application thereof UNIV SHAOXING 2012-09-05 CN claimed
CN-101648953-A Imidazo (1,2-b) pyrrolo (1,2-f) pyridazine derivative as well as preparation method and application thereof UNIV SHAOXING 2010-02-17 CN claimed
US-20030158038-A1 Guanidine compound and heat sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-08-21 US claimed
US-6329116-B1 CYAN COUPLER AND A DIAZONIUM SALT COMPOUND, EXCELLENT SHELF LIFE, IMAGE LIGHT-RESISTANCE, IMAGE FIXING, EXCELLENT HUE AND COLOR DENSITY, PREFERABLY MICROENCAPSULATED IN POLYURETHANE OR POLYUREA FUJI PHOTO FILM CO., LTD. (JP) 2001-12-11 US claimed
US-6228553-B1 SHELF LIFE, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2001-05-08 US claimed
EP-0484820-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-07-26 EP claimed
US-4831034-A 4-benzylpiperazines useful as neuroleptics RHONE-POULENC SANTE (FR) 1989-05-16 US claimed
EP-0256936-A1 4-Benzyl piperazine derivatives, their preparation and pharmaceutical compositions containing them RHONE-POULENC SANTE (FR) 1988-02-24 EP claimed