Sugi Predict

Sugi Predict / Compounds / Glycerin

Glycerin

Glycerin

SCHEMBL6520168

C(OCC1CO1)C1CO1.OCC(CO)(CO)CO.OCC(O)CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ ALDH1A1 P00352 6/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ TP53 P04637 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL23214508 0.90 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL42452 0.90 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL700209 0.90 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL3295078 0.90 TSHR (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL311322 0.88 TSHR (0.50) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL21799135 0.86 ALDH1A1 (0.45) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL27971376 0.86 TSHR (0.45) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL28776277 0.83 TSHR (0.42) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Glycerin SCHEMBL29029058 0.81 SMN1; SMN2 (0.48) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL27870592 0.81 TSHR (0.43) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005075527-A1 HYPERBRANCHED POLYMERS THE GENERAL HOSPITAL CORPORATION (US) 2005-08-18 — — WO disclosed