SCHEMBL6520216

SCHEMBL6520216

CC(O)(CO)NC(C)(O)CO

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358931 0.87 ALDH1A1 (0.30) ALDH1A1
SCHEMBL9734989 0.76
SCHEMBL6858851 0.73
SCHEMBL2866122 0.71
SCHEMBL26978248 0.71 TSHR (0.38) ALDH1A1
SCHEMBL6682309 0.71
SCHEMBL3361835 0.69
SCHEMBL3360719 0.69
SCHEMBL12478173 0.68
SCHEMBL42569 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916948-B2 Bis(1,3-dihydroxy-prop-2-yl) amine and derivatives thereof in the manufacture of polymers ISIS INNOVATION LIMITED (GB) 2005-07-12 US disclosed
US-20020052465-A1 Bis(1,3-dihydroxy-prop-2-yl) amine and derivatives thereof in the manufacture of polymers ISIS INNOVATION LIMITED (GB) 2002-05-02 US disclosed
EP-1159255-A2 BIS(1,3-DIHYDROXY-PROP-2-YL)AMINE AND DERIVATIVES THEREOF IN THE MANUFACTURE OF POLYMERS ISIS INNOVATION LIMITED (GB) 2001-12-05 EP disclosed
WO-2000055111-A2 BIS(1,3-DIHYDROXY-PROP-2-YL)AMINE AND DERIVATIVES THEREOF IN THE MANUFACTURE OF POLYMERS ISIS INNOVATION LIMITED (GB) 2000-09-21 WO disclosed
EP-0325762-B1 Macrocyclic chelating agents and chelates thereof BRACCO SPA (IT) 1995-03-22 EP disclosed
EP-0365541-B1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO S.p.A. (IT) 1992-08-12 EP disclosed
US-5132409-A Derivatives of 1,4,7,10-Tetraazacyclododecane BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1992-07-21 US disclosed
US-5066823-A Rearrangement reaction, contrast agent for radiology BRACCO INDUSTRIA CHEMICA S.P.A. (IT) 1991-11-19 US disclosed
EP-0440606-A1 MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) 1991-08-14 EP disclosed
EP-0365541-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. BRACCO IND CHIMICA SPA (IT) 1990-05-02 EP disclosed
EP-0325762-A1 Macrocyclic chelating agents and chelates thereof BRACCO S.p.A. (IT) 1989-08-02 EP disclosed
WO-1989005802-A1 MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1989-06-29 WO disclosed
WO-1988009328-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1988-12-01 WO disclosed
US-4503252-A Process for the preparation of serinol and of serinol derivatives, and products obtained therefrom EPROVA AKTIENGESELLSCHAFT (CH) 1985-03-05 US disclosed
EP-0025083-B1 PROCESS FOR THE PREPARATION OF SERINOL AND SERINOL DERIVATIVES EPROVA Aktiengesellschaft (CH) 1982-02-03 EP disclosed
EP-0025083-A2 Process for the preparation of Serinol and Serinol derivatives EPROVA Aktiengesellschaft (CH) 1981-03-18 EP disclosed