SCHEMBL6520544

SCHEMBL6520544

CC(=O)c1c(SSc2c(C(C)=O)c(C(C)=O)c(C(C)=O)c(C(C)=O)c2C(C)=O)c(C(C)=O)c(C(C)=O)c(C(C)=O)c1C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 1/20 0.37
THRB P10828 1/20 0.36
EGFR P00533 1/20 0.32
SRC P12931 1/20 0.32
CA5A P35218 1/20 0.32
USP2 O75604 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BRD4 O60885 1/20 0.31
BRPF1 P55201 1/20 0.31
CREBBP Q92793 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648663 0.78 SMN1; SMN2 (0.44) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL7262130 0.67 SMN1; SMN2 (0.50) CYP3A4MEN1KMT2AHPGDTHRB
SCHEMBL6524772 0.65 CYP1A2 (0.36) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL6512921 0.65 CYP3A4 (0.38) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL6519336 0.62 CYP3A4 (0.36) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL6517438 0.62 CYP3A4 (0.36) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL3127761 0.62 CYP3A4 (0.41) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL19149846 0.62 CYP3A4 (0.48) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL6023652 0.62 CYP3A4 (0.48) CYP3A4MEN1KMT2AHPGDCYP1A2
SCHEMBL11893177 0.60 CYP3A4 (0.46) CYP3A4MEN1KMT2AHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583229-B2 Core layer is formed by vulcanizing and press molding a rubber composition of a base rubber, crosslinking agent, organic peroxide, filler, and a benzene mercaptan, polysufide, or metal sulfide; exceptional rebound, flight, shot feel SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-06-24 US claimed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-6583229-B2 Core layer is formed by vulcanizing and press molding a rubber composition of a base rubber, crosslinking agent, organic peroxide, filler, and a benzene mercaptan, polysufide, or metal sulfide; exceptional rebound, flight, shot feel SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-06-24 US disclosed
US-20030050136-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-03-13 US disclosed