SCHEMBL1648663

SCHEMBL1648663

CC(=O)c1cc(C(C)=O)c(C(C)=O)c(SSc2c(C(C)=O)c(C(C)=O)cc(C(C)=O)c2C(C)=O)c1C(C)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
CYP3A4 P08684 6/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 2/20 0.38
THRB P10828 1/20 0.36
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.32
EGFR P00533 1/20 0.32
SRC P12931 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NSD2 O96028 1/20 0.32
POLB P06746 1/20 0.32
MCL1 Q07820 1/20 0.32
CYP1A2 P05177 1/20 0.32
CA5A P35218 1/20 0.32
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262130 0.81 SMN1; SMN2 (0.50) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL6520544 0.78 CYP3A4 (0.42) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL7263483 0.75 SMN1; SMN2 (0.44) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL7269156 0.74 SMN1; SMN2 (0.60) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL7267961 0.73 SMN1; SMN2 (0.43) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL6515472 0.73 CA5A (0.46) SMN1; SMN2KMT2AHPGDHTTMAPT
SCHEMBL28572602 0.72 CA5A (0.50) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL10445944 0.70 CYP3A4 (0.41) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL27970836 0.70 KMT2A (0.41) SMN1; SMN2CYP3A4MEN1KMT2AHPGD
SCHEMBL27694250 0.70 KMT2A (0.43) SMN1; SMN2CYP3A4MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583229-B2 Core layer is formed by vulcanizing and press molding a rubber composition of a base rubber, crosslinking agent, organic peroxide, filler, and a benzene mercaptan, polysufide, or metal sulfide; exceptional rebound, flight, shot feel SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-06-24 US claimed
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed
US-6583229-B2 Core layer is formed by vulcanizing and press molding a rubber composition of a base rubber, crosslinking agent, organic peroxide, filler, and a benzene mercaptan, polysufide, or metal sulfide; exceptional rebound, flight, shot feel SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-06-24 US disclosed
US-20030050136-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-03-13 US disclosed