Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL11869376 | 0.89 | GSK3B (0.65) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL17729108 | 0.83 | GSK3B (0.68) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL10725622 | 0.80 | GSK3B (0.48) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL28946377 | 0.79 | GSK3B (0.75) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL8693407 | 0.79 | GSK3B (0.56) | GSK3BCASP3CASP2CASP7CASP6 | |
| Tetrabuthylammonium SCHEMBL8967570 | 0.79 | GSK3B (0.56) | GSK3BCASP3CASP2CASP7CASP6 | |
| Tetrabuthylammonium SCHEMBL28914816 | 0.77 | GSK3B (0.54) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL28322032 | 0.77 | GSK3B (0.48) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL28193801 | 0.77 | GSK3B (0.79) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL27955087 | 0.77 | GSK3B (0.79) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296870-B2 | Modification of surfaces with nanoparticles | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-03-29 | — | — | US | disclosed |
| US-20110059264-A1 | MODIFICATION OF SURFACES WITH NANOPARTICLES | NATIONAL SCIENCE FOUNDATION | 2011-03-10 | — | — | US | disclosed |