SCHEMBL6521752

SCHEMBL6521752

FC(F)(F)CCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.58
DRD2 P14416 2/20 0.43
DRD4 P21917 1/20 0.43
DRD3 P35462 1/20 0.43
HTR2B P41595 3/20 0.38
HTR7 P34969 2/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
HTR2A P28223 2/20 0.38
HTR2C P28335 2/20 0.38
CYP2D6 P10635 2/20 0.33
HRH1 P35367 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5366733 0.84 PNMT (0.72) PNMTDRD2DRD4DRD3HTR2B
SCHEMBL4155281 0.83 PNMT (0.62) PNMTDRD2DRD4DRD3HTR2B
SCHEMBL7603814 0.83 PNMT (0.70) PNMTDRD2DRD4DRD3HTR2B
SCHEMBL9859906 0.83 PNMT (0.70) PNMTDRD2DRD4DRD3HTR2B
SCHEMBL7609046 0.83 PNMT (0.70) PNMTDRD2DRD4DRD3HTR2B
SCHEMBL6558685 0.83 PNMT (0.70) PNMTDRD2DRD4DRD3HTR2B
Hydrochloric Acid SCHEMBL5348072 0.81 PNMT (0.68) PNMTDRD2DRD4DRD3HTR2B
Hydrochloric Acid SCHEMBL5357887 0.81 PNMT (0.68) PNMTDRD2DRD4DRD3HTR2B
Hydrochloric Acid SCHEMBL9245137 0.81 PNMT (0.68) PNMTDRD2DRD4DRD3HTR2B
SCHEMBL6674911 0.81 PNMT (0.68) PNMTDRD2DRD4DRD3HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107266334-B Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator 大东凯米克斯株式会社 2020-04-24 CN disclosed
CN-104684888-A Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator DAITO CHEMIX CORP 2015-06-03 CN disclosed
US-6908974-B2 Catalyst composition and a process for preparing linear, isotactic polymers RIEGER BERNHARD (DE) 2005-06-21 US disclosed
US-6790922-B2 OLEFIN HOMO/COPOLYMERS, FORMED BY GAS PHASE POLYMERIZATION IN THE PRESENCE OF POLYMERIZATION CATALYSTS AND ACTIVATORS, USED AS FIBERS, SHEETS AND MOLDINGS HAVING IMPACT STRENGTH Rieger, Bernhard (DE) 2004-09-14 US disclosed
US-6576726-B1 Titanium, zirconium, hafnium, vanadium, niobium, or tantalum metal cyclopentylindenyl complex and alumoxane activator RIEGER BERNHARD (DE) 2003-06-10 US disclosed
US-6555643-B1 Linear, isotactic polymers, process for preparing same, and use thereof RIEGER BERNHARD (DE) 2003-04-29 US disclosed
EP-1302484-A2 Linear, isotactic polymers, process for preparing same, and use thereof Rieger, Bernhard, Prof. Dr. (DE) 2003-04-16 EP disclosed
EP-1070089-B1 LINEAR, ISOTACTIC POLYMERS, PROCESS FOR PREPARING SAME, AND USE THEREOF RIEGER BERNHARD PROF DR (DE) 2003-03-19 EP disclosed
EP-1070087-B1 A CATALYST COMBINATION AND A PROCESS FOR PREPARING LINEAR, ISOTACTIC POLYMERS RIEGER BERNHARD PROF DR (DE) 2002-07-03 EP disclosed
EP-1178057-A2 A catalyst composition and a process for preparing linear, isotactic polymers Rieger, Bernhard, Prof. Dr. (DE) 2002-02-06 EP disclosed