SCHEMBL6522063

SCHEMBL6522063

CC(C)(C#N)/N=N\C(C)(C)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL31152866 1.00
SCHEMBL6562703 1.00
SCHEMBL120 1.00
Water SCHEMBL21518539 1.00
SCHEMBL5199999 1.00
SCHEMBL122 1.00
SCHEMBL10454455 0.96
Hydrochloric Acid SCHEMBL9508595 0.96
Lithium SCHEMBL30850376 0.96
Potassium SCHEMBL31187922 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320228-A1 PYRIDO[3,2-D]PYRIMIDINES AS HPK1 INHIBITORS MERCK PATENT GMBH (DE) 2025-10-16 US disclosed
EP-4522618-A1 TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS Merck Patent GmbH (DE) 2025-03-19 EP disclosed
EP-4507789-A1 PYRIDO[3,2-D]PYRIMIDINES AS HPK1 INHIBITORS Merck Patent GmbH (DE) 2025-02-19 EP disclosed
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS MERCK HEALTHCARE KGAA (DE) 2024-01-25 US disclosed
US-11827732-B2 Amphiphilic branched copolymer drilling additive SAUDI ARABIAN OIL COMPANY (SA) 2023-11-28 US disclosed
WO-2023220541-A1 TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS MERCK PATENT GMBH (DE) 2023-11-16 WO disclosed
WO-2023201185-A1 PYRIDO[3,2-D]PYRIMIDINES AS HPK1 INHIBITORS MERCK PATENT GMBH (DE) 2023-10-19 WO disclosed
US-11732177-B2 Cement slurries, cured cement and methods of making and use of these SAUDI ARABIAN OIL COMPANY (SA) 2023-08-22 US disclosed
US-20220243113-A1 DRILLING FLUIDS AND METHODS OF MAKING AND USE THEREOF SAUDI ARABIAN OIL COMPANY (SA) 2022-08-04 US disclosed
US-20220144703-A1 CEMENT SLURRIES, CURED CEMENT AND METHODS OF MAKING AND USE OF THESE SAUDI ARABIAN OIL COMPANY (SA) 2022-05-12 US disclosed
US-20220145159-A1 CEMENT SLURRIES, CURED CEMENT AND METHODS OF MAKING AND USE OF THESE SAUDI ARABIAN OIL COMPANY (SA) 2022-05-12 US disclosed
EP-2976339-B1 GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS MERCK SHARP & DOHME (US) 2018-06-27 EP disclosed
US-9957264-B2 Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors MERCK SHARP & DOHME CORP. (US) 2018-05-01 US disclosed
US-20160272632-A1 GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2016-09-22 US disclosed
EP-2976339-A1 GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS Merck Sharp & Dohme Corp. (US) 2016-01-27 EP disclosed
WO-2014146491-A1 GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-09-25 WO disclosed
WO-2014146249-A1 GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-09-25 WO disclosed
US-6933078-B2 Crosslinked polymer electrolytes and method of making such crosslinked polymers VALENCE TECHNOLOGY, INC. (US) 2005-08-23 US disclosed
WO-2004057690-A2 CR0SSLINKED POLYMER ELECTROLTYES AND METHOD OF MAKING SUCH CROSSLINKED POLYMERS VALENCE TECHNOLOGY, INC. (US) 2004-07-08 WO disclosed
US-20040122178-A1 e.g., methoxypolyoxyethylene (9 units) monomethacrylate crosslinked with polytriethoxyvinylsilane - LiBF4 solvate: highly non-crystalline; rechargeable batteries VALENCE TECHNOLOGY, INC. 2004-06-24 US disclosed