Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15124169 | 0.98 | MMP1 (0.43) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL15124168 | 0.98 | MMP1 (0.43) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| SCHEMBL10268571 | 0.95 | MMP1 (0.39) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL15124307 | 0.94 | MMP1 (0.39) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL319091 | 0.94 | MMP1 (0.39) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| SCHEMBL2687128 | 0.88 | DPP4 (0.42) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| SCHEMBL15130699 | 0.81 | CYP3A4 (0.37) | MMP1MMP3DPP4CYP3A4TSHR | |
| SCHEMBL4701570 | 0.81 | CYP3A4 (0.37) | MMP1MMP3DPP4CYP3A4TSHR | |
| SCHEMBL12494329 | 0.79 | SMN1; SMN2 (0.44) | MMP1MMP3DPP4ALDH1A1CYP3A4 | |
| SCHEMBL12525641 | 0.79 | SMN1; SMN2 (0.44) | MMP1MMP3DPP4ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182046-A1 | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds | WU JING (US) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182046-A1 | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds | BACE1, APP, BACE2 | MMP1 1728/4885MMP3 1471/4885DPP4 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.