Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386301 | 0.85 | CA1 (0.76) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL29658293 | 0.85 | CA1 (0.76) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL9244059 | 0.77 | KDM4E (0.46) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL9466149 | 0.74 | KMT2A (0.62) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL4108427 | 0.71 | CA1 (1.00) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL23718228 | 0.71 | MAPT (0.61) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL29433315 | 0.71 | CA1 (0.66) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL28686838 | 0.71 | CA1 (0.66) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL6951753 | 0.69 | SHMT2 (0.52) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL8381514 | 0.69 | GAA (0.69) | CA1CA2CA9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6200738-B1 | SIMPLIFYING PROCESSING BY REMOVAL OF RESIDUAL SILVER USING IMAGE INFORMATION OF A WAVELENGTH REGION, IN WHICH A DYE IMAGEWISE OBTAINED UPON DEVELOPMENT HAS NO ABSORPTION, E.G., IN THE INFRARED WAVELENGTH REGION; SHORTENING THE TIME | KONICA CORPORATION (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0997776-A1 | Image forming method | KONICA CORPORATION (JP) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| US-5478720-A | Containing a monomethine-, a trimethine-cyanine dye and a supersensitizer; storage stability, low fogging, high speed | KONICA CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| US-5338650-A | Number and arrangement of perforations; thickness; noncurling; useful in small, lightweight cameras | KONICA CORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0556812-A1 | A silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1993-08-25 | — | — | EP | disclosed |