Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818655 | 0.91 | SMN1; SMN2 (0.63) | L3MBTL1SMN1; SMN2ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL12313445 | 0.89 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1MMP12MMP13 | |
| SCHEMBL29886938 | 0.89 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL6519323 | 0.89 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1HSD17B10CYP2C19 | |
| Water SCHEMBL18832247 | 0.89 | SMN1; SMN2 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL9145969 | 0.89 | SMN1; SMN2 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL9870305 | 0.88 | AKR1B1 (0.51) | L3MBTL1SMN1; SMN2ALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL23693626 | 0.85 | PARP1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL23693571 | 0.85 | AHR (0.53) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL6526017 | 0.85 | MEN1 (0.50) | L3MBTL1ALDH1A1CYP2C19TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |