SCHEMBL6522928

SCHEMBL6522928

CCC(C(=O)O)n1c(=O)[nH]c(=O)n(C(CC)C(=O)O)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
APEX1 P27695 1/20 0.36
KDM4E B2RXH2 3/20 0.32
MEN1 O00255 2/20 0.32
CYP2C19 P33261 2/20 0.32
BLM P54132 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
PTPN7 P35236 1/20 0.32
RECQL P46063 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29251519 0.90 POLB (0.36) POLBAPEX1KDM4EMEN1CYP2C19
SCHEMBL6525463 0.86 POLB (0.41) POLBKDM4EMEN1CYP2C19BLM
SCHEMBL6525042 0.85 POLB (0.40) POLBKDM4EMEN1CYP2C19BLM
SCHEMBL6518036 0.81 APEX1 (0.32) APEX1
SCHEMBL6521018 0.80 APEX1 (0.33) APEX1KDM4EHSD17B10MDM2B3GNT2
SCHEMBL7344992 0.80 POLB (0.41) POLBKDM4EMEN1CYP2C19BLM
SCHEMBL6518031 0.79 HSD17B10 (0.32) POLBAPEX1MEN1KMT2ATDP1
SCHEMBL27801894 0.75 POLB (0.59) POLBKDM4EMEN1KMT2AMDM2
SCHEMBL6526383 0.74 CSNK2A2 (0.37) POLBAPEX1KDM4EMEN1CYP2C19
SCHEMBL9432792 0.73 POLB (0.62) POLBKDM4EMDM2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6841305-B2 High temperature, storage stability MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-01-11 US disclosed
US-20020009652-A1 High temperature, storage stability MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-01-24 US disclosed
EP-1160899-A2 Non-aqueous electrolyte battery and non-aqueous electrolyte MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-12-05 EP disclosed