Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6523261 | 1.00 | PRKDC (0.49) | PRKDCKDM1ALCKFYNMAPT | |
| SCHEMBL6523254 | 1.00 | PRKDC (0.49) | PRKDCKDM1ALCKFYNMAPT | |
| SCHEMBL30655454 | 0.84 | MAPT (0.37) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7080563 | 0.82 | MAPT (0.35) | MAPTALDH1A1PRNPGAAALOX12 | |
| SCHEMBL7080565 | 0.82 | MAPT (0.35) | MAPTALDH1A1PRNPGAAALOX12 | |
| SCHEMBL6486683 | 0.76 | MEN1 (0.45) | MAPTALDH1A1GAAHPGDLMNA | |
| SCHEMBL6486687 | 0.76 | MEN1 (0.45) | MAPTALDH1A1GAAHPGDLMNA | |
| SCHEMBL6132092 | 0.75 | GAA (0.55) | MAPTALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL6132093 | 0.75 | GAA (0.55) | MAPTALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL8357109 | 0.74 | ABCG2 (0.47) | MAPTALDH1A1GAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252569-B1 | ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS | JULIUS MAXIMILIANS UNIVERSITÄT WÜRZBURG (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-8877718-B2 | Antiinfective and antitumoral compounds isolated from tropical lianas | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2014-11-04 | — | — | US | disclosed |
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | NCL, SYNCRIP, MYC | PRKDC 1894/4885KDM1A 3231/4885LCK 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.