Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 3/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.58 |
| ▸ | HBB | P68871 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PRNP | P04156 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199957 | 0.91 | USP2 (0.58) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| Hydrochloric Acid SCHEMBL6201590 | 0.90 | KMT2A (0.59) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL1153070 | 0.86 | USP2 (0.75) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL23795497 | 0.80 | MBNL1 (0.75) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL6782798 | 0.80 | ADORA2A (0.82) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL23904131 | 0.79 | MBNL1 (0.77) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL6523295 | 0.79 | USP2 (0.65) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL23904123 | 0.79 | ADORA2A (0.78) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL23904654 | 0.79 | ADORA2A (0.78) | ADORA2AUSP2TP53CYP3A4CASP1 | |
| SCHEMBL7545214 | 0.79 | ADORA2A (0.78) | ADORA2AUSP2TP53CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354533-A1 | ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | CERUS CORPORATION (US) | 2016-12-08 | — | — | US | disclosed |
| EP-1508345-B1 | System and method for the reduction of small organic compounds from blood products | CERUS CORP (US) | 2013-09-25 | — | — | EP | disclosed |
| EP-1508345-A1 | Absorbents and devices for the reduction of small organic compounds from blood products | Cerus Corporation (US) | 2005-02-23 | — | — | EP | disclosed |
| US-20040185553-A9 | ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | HEI DEREK J (US) | 2004-09-23 | — | — | US | disclosed |
| US-20020094568-A1 | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use | HEI DEREK J (US) | 2002-07-18 | — | — | US | disclosed |
| US-20010018179-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION | 2001-08-30 | — | — | US | disclosed |
| US-20010009756-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | CERUS CORPORATION | 2001-07-26 | — | — | US | disclosed |