⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155737 | 0.81 | — | — | |
| SCHEMBL6877668 | 0.73 | — | — | |
| SCHEMBL2211821 | 0.72 | — | — | |
| SCHEMBL9715042 | 0.72 | — | — | |
| SCHEMBL10698294 | 0.71 | — | — | |
| SCHEMBL65532 | 0.70 | — | — | |
| SCHEMBL10535413 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL510939 | 0.68 | — | — | |
| SCHEMBL545327 | 0.67 | — | — | |
| SCHEMBL29107385 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690419-B | Silicon-containing prepolymer and silicone hydrogel biomaterial containing same | ZHAN QIANQING | 2014-05-07 | — | — | CN | disclosed |
| CN-102690419-A | Silicon-containing prepolymer and silicone hydrogel biomaterial containing same | QIANQING ZHAN | 2012-09-26 | — | — | CN | disclosed |
| EP-1604231-A1 | PHOTOCHROMIC OCULAR DEVICES | TRANSITIONS OPTICAL, INC. (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004086103-A1 | PHOTOCHROMIC OCULAR DEVICES | TRANSITIONS OPTICAL INC. (US) | 2004-10-07 | — | — | WO | disclosed |