Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777675 | 0.94 | SMN1; SMN2 (0.36) | PSMB8PSMB5KMT2ASMN1; SMN2TSHR | |
| SCHEMBL34383 | 0.94 | SMN1; SMN2 (0.36) | PSMB8PSMB5KMT2ASMN1; SMN2TSHR | |
| Ethylene Glycol SCHEMBL6129445 | 0.93 | TSHR (0.40) | PSMB8PSMB5KMT2ASMN1; SMN2TSHR | |
| SCHEMBL34437 | 0.92 | PSMB8 (0.34) | PSMB8PSMB5KMT2ASMN1; SMN2ALOX12 | |
| SCHEMBL29945244 | 0.92 | SMN1; SMN2 (0.36) | PSMB8PSMB5KMT2ASMN1; SMN2TSHR | |
| Ethylene Glycol SCHEMBL999673 | 0.92 | PSMB8 (0.36) | PSMB8PSMB5MGLL | |
| SCHEMBL16130614 | 0.91 | SMN1; SMN2 (0.36) | PSMB8PSMB5KMT2ASMN1; SMN2ALOX12 | |
| SCHEMBL290461 | 0.90 | SMN1; SMN2 (0.40) | PSMB8PSMB5KMT2ASMN1; SMN2ALOX12 | |
| Ethylene Glycol SCHEMBL15201496 | 0.90 | KMT2A (0.43) | PSMB8PSMB5KMT2ASMN1; SMN2PRKCA | |
| SCHEMBL15760633 | 0.90 | PSMB8 (0.34) | PSMB8PSMB5KMT2ASMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019171215-A1 | SEALANT FOAM COMPOSITIONS FOR LUNG APPLICATIONS | ETHICON LLC (PR) | 2019-09-12 | — | — | WO | disclosed |
| EP-1594459-A2 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG (CH) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004060346-A2 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG (CH) | 2004-07-22 | — | — | WO | disclosed |