Ethylene Glycol

Ethylene Glycol

SCHEMBL999673

O=C(CCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 2/20 0.36
PSMB5 P28074 1/20 0.36
MGLL Q99685 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43576 0.94 PSMB8 (0.35) PSMB8PSMB5MGLLLMNA
Ethylene Glycol SCHEMBL2467342 0.93 PSMB8 (0.35) PSMB8PSMB5MGLLLMNA
Ethylene Glycol SCHEMBL6523939 0.92 PSMB8 (0.34) PSMB8PSMB5MGLL
SCHEMBL2607886 0.92 PSMB8 (0.38) PSMB8PSMB5MGLLLMNA
SCHEMBL31522720 0.91 PSMB8 (0.34) PSMB8PSMB5MGLLLMNA
SCHEMBL2607893 0.89 PSMB8 (0.35) PSMB8PSMB5MGLL
Ethylene Glycol SCHEMBL28215416 0.89 ALDH1A1 (0.39) PSMB8PSMB5
SCHEMBL34437 0.88 PSMB8 (0.34) PSMB8PSMB5MGLL
Urea SCHEMBL4909809 0.88 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL14644916 0.88 PSMB8 (0.33) PSMB8PSMB5MGLLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US claimed
US-12012619-B2 Methods of use for an NADPH-regeneration system based on a monomeric isocitrate dehydrogenase INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2024-06-18 US claimed
US-20230143972-A1 NADPH-REGENERATION SYSTEM BASED ON MONOMERIC ISOCITRATE DEHYDROGENASE AND USE THEREOF INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2023-05-11 US claimed
US-20220370635-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY SIXFOLD BIOSCIENCE LTD (GB) 2022-11-24 US claimed
US-20220267742-A1 NADPH-REGENERATION SYSTEM BASED ON MONOMERIC ISOCITRATE DEHYDROGENASE AND USE THEREOF INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2022-08-25 US claimed
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2022-06-14 US claimed
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-10-28 US claimed
US-9717733-B2 Edible plant-derived microvesicle compositions including conjugated therapeutic agents and methods for using the same UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2017-08-01 US claimed
US-20160045448-A1 EDIBLE PLANT-DERIVED MICROVESICLE COMPOSITIONS INCLUDING CONJUGATED THERAPEUTIC AGENTS AND METHODS FOR USING THE SAME UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION 2016-02-18 US claimed
US-7238794-B2 Organic conductor FUJI XEROX CO., LTD. (JP) 2007-07-03 US claimed
US-6995971-B2 Capacitors including interacting separators and surfactants MEDTRONIC, INC. (US) 2006-02-07 US claimed
US-20040240156-A1 Capacitors including interacting separators and surfactants MEDTRONIC, INC. 2004-12-02 US claimed
US-20030170692-A1 Organic conductor FUJI XEROX CO., LTD. (JP) 2003-09-11 US claimed
EP-1324352-A2 Organic conductor FUJI XEROX CO., LTD. (JP) 2003-07-02 EP claimed
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US disclosed
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP disclosed
EP-3859335-B1 MEMBRANE CARRIER FOR TEST KIT AND TEST KIT DENKA COMPANY LTD (JP) 2024-10-02 EP disclosed
EP-1072688-A1 METHOD FOR IN VIVO DETECTING TARGET PROTEIN GENE BY DRUG Hidaka, Hiroyoshi (JP) 2001-01-31 EP disclosed
US-5916585-A POLYMERIC SURFACTANTS ATTACHED ONTO THE SURFACES OF A SUPPORT MEMBER AND COVALENTLY CROSS-LINKED THEREON TO FORM A FIRST LAYER. HYDROPHILIC POLYMERS ARE THEN ATTACHED TO THE FIRST LAYER ON THE SUPPORT MEMBER TO FORM A SECOND LAYER THEREON. GORE ENTERPRISE HOLDINGS, INC. (US) 1999-06-29 US disclosed
EP-0870826-A1 NOVEL PROTEIN AND MONOCLONAL ANTIBODY SPECIFIC THERETO FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1998-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN PSMB8 1954/4885PSMB5 1237/4885MGLL 4186/4885
US-20220370635-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN PSMB8 1954/4885PSMB5 1237/4885MGLL 4186/4885
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN PSMB8 1954/4885PSMB5 1237/4885MGLL 4186/4885
US-20030170692-A1 Organic conductor DNMT1, DNMT3A, POLN PSMB8 4855/4885PSMB5 4884/4885MGLL 4740/4885
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN PSMB8 1954/4885PSMB5 1237/4885MGLL 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.