SCHEMBL6523967

SCHEMBL6523967

O=S(O)c1ccc(S)c(Sc2ccccc2)c1.[NaH]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.36
MAPT P10636 5/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NSD2 O96028 1/20 0.32
MAPK1 P28482 1/20 0.32
HPGD P15428 4/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 4/20 0.31
KMT2A Q03164 3/20 0.31
PDE7A Q13946 2/20 0.31
MEN1 O00255 2/20 0.31
BLM P54132 1/20 0.31
ADORA2A P29274 1/20 0.31
PDE7B Q9NP56 1/20 0.31
LMNA P02545 2/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513921 0.98 SIRT1 (0.37) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL6523979 0.97 SIRT1 (0.36) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL6516886 0.97 SIRT1 (0.36) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL6513064 0.84 SIRT1 (0.38) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL28040291 0.81 SIRT1 (0.36) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL6523970 0.81 PDE7A (0.34) SIRT1MAPTKDM4ENSD2MAPK1
Zinc Ion SCHEMBL6516889 0.81 PDE7A (0.34) SIRT1MAPTKDM4ENSD2MAPK1
SCHEMBL6512746 0.76 HPGD (0.50) SIRT1MAPTTDP1KDM4EHPGD
SCHEMBL6519473 0.73 HPGD (0.52) SIRT1MAPTTDP1KDM4EHPGD
SCHEMBL6512749 0.72 HPGD (0.50) SIRT1MAPTTDP1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005505-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005507-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed