SCHEMBL6524276

SCHEMBL6524276

CCOCCOC(C)(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL816642 0.81 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL31474633 0.79 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL239710 0.78 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL30898760 0.77 ALDH1A1 (0.36) ALDH1A1TSHRTHRB
SCHEMBL30898757 0.77 ALDH1A1 (0.36) ALDH1A1TSHRTHRB
SCHEMBL14213165 0.77 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL4137675 0.76 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL11593049 0.76 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL4330955 0.75 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL14649741 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703759-B2 Fused heterocyclic compounds as ion channel modulators GILEAD SCIENCES, INC. (US) 2014-04-22 US disclosed
EP-0924788-B1 Polymeric solid electrolyte and electrochemical element using the same SHARP KK (JP) 2005-02-16 EP disclosed
US-6465135-B1 Polymeric solid electrolyte and electrochemical element using the same SHARP KABUSHIKI KAISHA (JP) 2002-10-15 US disclosed
EP-0924788-A1 Polymeric solid electrolyte and electrochemical element using the same Sharp Kabushiki Kaisha (JP) 1999-06-23 EP disclosed