⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127902 | 0.87 | ALDH1A1 (0.34) | — | |
| SCHEMBL7841178 | 0.75 | — | — | |
| SCHEMBL31489841 | 0.75 | — | — | |
| SCHEMBL28165954 | 0.75 | — | — | |
| SCHEMBL10305653 | 0.75 | — | — | |
| SCHEMBL14303161 | 0.75 | — | — | |
| SCHEMBL2473751 | 0.75 | — | — | |
| SCHEMBL4881353 | 0.75 | — | — | |
| SCHEMBL4828775 | 0.75 | — | — | |
| SCHEMBL4375559 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | claimed |
| EP-0136593-A2 | Novel halopyridines and methods of making | THE DOW CHEMICAL COMPANY (US) | 1985-04-10 | — | — | EP | claimed |
| US-11332455-B2 | α,β-unsaturated amide compound | KYOWA KIRIN CO., LTD. (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20210380551-A1 | ALPHA,BETA-UNSATURATED AMIDE COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| WO-2021138298-A1 | MALT1 MODULATORS AND USES THEREOF | RHEOS MEDICINES, INC. (US) | 2021-07-08 | — | — | WO | disclosed |
| US-20170204073-A1 | COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE | PTC THERAPEUTICS, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-9611230-B2 | 1,3,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease | PTC THERAPEUTICS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| EP-2494975-A1 | Compounds and methods for promoting smoking cessation | Research Triangle Institute (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120208820-A1 | DIAZABICYCLIC CENTRAL NERVOUS SYSTEM ACTIVE AGENTS | SCHRIMPF MICHAEL R (US) | 2012-08-16 | — | — | US | disclosed |
| US-8119635-B2 | Diazabicyclic central nervous system active agents | ABBOTT LABORATORIES (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2404923-A1 | 7-azabicyclo[2.2.1]heptane derivatives useful for promoting smoking cessation | RESEARCH TRIANGLE INSTITUTE (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |
| WO-1998037082-A1 | 7a-HETEROCYCLE-SUBSTITUTED HEXAHYDRO-1H-PYRROLIZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1998-08-27 | — | — | WO | disclosed |
| US-5733912-A | NERVOUS SYSTEM DISORDERS IN NERVE CELLS | ABBOTT LABORATORIES (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0136593-A3 | NOVEL HALOPYRIDINES AND METHODS OF MAKING | THE DOW CHEMICAL COMPANY (US) | 1988-03-30 | — | — | EP | disclosed |
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0136593-A2 | Novel halopyridines and methods of making | THE DOW CHEMICAL COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| EP-0136593-A2 | Novel halopyridines and methods of making | THE DOW CHEMICAL COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |