Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240366 | 0.79 | — | — | |
| SCHEMBL301895 | 0.79 | — | — | |
| SCHEMBL933721 | 0.79 | — | — | |
| SCHEMBL11457956 | 0.77 | TSHR (0.39) | TSHRSLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL11455456 | 0.77 | TSHR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| Hydrochloric Acid SCHEMBL27728870 | 0.77 | TSHR (0.39) | TSHRSLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL14590461 | 0.76 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1CHRM2 | |
| SCHEMBL7712918 | 0.76 | ALDH1A1 (0.38) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL6129572 | 0.76 | GSR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL221495 | 0.76 | SLC1A2 (0.46) | TSHRSLC1A3SLC1A2SLC1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050089850-A1 | Genotyping by liquid chromatographic analysis of short nucleic acid fragments | KECK GRADUATE INSTITUTE | 2005-04-28 | — | — | US | disclosed |
| WO-2003066802-A9 | GENE EXPRESSION ANALYSIS USING NICKING AGENTS | KECK GRADUATE INST (US) | 2004-12-16 | — | — | WO | disclosed |
| EP-1470250-A2 | GENE EXPRESSION ANALYSIS USING NICKING AGENTS | Keck Graduate Institute (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2004067764-A2 | NUCLEIC ACID SEQUENCING USING NICKING AGENTS | KECK GRADUATE INSTITUTE (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004067726-A2 | ISOTHERMAL REACTIONS FOR THE AMPLIFICATION OF OLIGONUCLEOTIDES | KECK GRADUATE INSTITUTE (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004067765-A2 | ORGANISM FINGERPRINTING USING NICKING AGENTS | KECK GRADUATE INSTITUTE (US) | 2004-08-12 | — | — | WO | disclosed |
| EP-1409732-A2 | AMPLIFICATION OF NUCLEIC ACID FRAGMENTS USING NICKING AGENTS | Keck Graduate Institute (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003080645-A2 | AMPLIFICATION OF NUCLEIC ACID FRAGMENTS USING NICKING AGENTS | KECK GRADUATE INSTITUTE (US) | 2003-10-02 | — | — | WO | disclosed |
| US-20030165911-A1 | Gene expression analysis using nicking agents | KECK GRADUATE INSTITUTE (US) | 2003-09-04 | — | — | US | disclosed |
| WO-2003066802-A2 | GENE EXPRESSION ANALYSIS USING NICKING AGENTS | KECK GRADUATE INSTITUTE (US) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003008642-A2 | AMPLIFICATION OF NUCLEIC ACID FRAGMENTS USING NICKING AGENTS | KECK GRADUATE INSTITUTE (US) | 2003-01-30 | — | — | WO | disclosed |
| WO-2002028501-A1 | GENOTYPING BY LIQUID CHROMATOGRAPHIC ANALYSIS OF SHORT NUCLEIC ACID FRAGMENTS | KECK GRADUATE INSTITUTE (US) | 2002-04-11 | — | — | WO | disclosed |