SCHEMBL6524754

SCHEMBL6524754

NC(=O)c1ccc(S)c([N+](=O)[O-])c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.65
GAA P10253 4/20 0.54
ALDH1A1 P00352 3/20 0.54
PKM P14618 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CASP6 P55212 1/20 0.53
LMNA P02545 7/20 0.53
TSHR P16473 3/20 0.52
SMN1; SMN2 Q16637 4/20 0.49
POLB P06746 2/20 0.49
ATM Q13315 1/20 0.49
CTPS1 P17812 1/20 0.49
MAPT P10636 4/20 0.48
HTT P42858 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512576 0.98 PARP1 (0.63) PARP1GAAALDH1A1PKML3MBTL1
SCHEMBL6513138 0.98 PARP1 (0.63) PARP1GAAALDH1A1PKML3MBTL1
SCHEMBL6513143 0.98 PARP1 (0.63) PARP1GAAALDH1A1PKML3MBTL1
Zinc Ion SCHEMBL6512579 0.98 PARP1 (0.63) PARP1GAAALDH1A1PKML3MBTL1
SCHEMBL6513141 0.98 PARP1 (0.63) PARP1GAAALDH1A1PKML3MBTL1
SCHEMBL6515592 0.85 CASP6 (0.72) CASP6LMNATSHR
SCHEMBL6512645 0.84 CASP6 (0.70) CASP6LMNATSHR
SCHEMBL6512633 0.84 CASP6 (0.70) CASP6LMNATSHR
Zinc Ion SCHEMBL6523817 0.84 CASP6 (0.70) CASP6LMNATSHR
SCHEMBL6523810 0.84 CASP6 (0.70) CASP6LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036821-B1 Process for the preparation of thiazine-indigo compounds and of new intermediates therefor CLARIANT FINANCE BVI LTD (VG) 2004-01-28 EP claimed
EP-1036821-A1 Process for the preparation of thiazine-indigo compounds and of new intermediates therefor Clariant Finance (BVI) Limited (VG) 2000-09-20 EP claimed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed