SCHEMBL6524792

SCHEMBL6524792

COC(=O)c1ccc(S)c(N)c1.[Zn]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.64
ALDH1A1 P00352 9/20 0.64
MAPT P10636 9/20 0.64
HPGD P15428 7/20 0.64
GAA P10253 4/20 0.64
HSD17B10 Q99714 4/20 0.64
GLA P06280 1/20 0.64
CASP1 P29466 1/20 0.64
CASP7 P55210 1/20 0.64
ATM Q13315 1/20 0.64
USP2 O75604 1/20 0.54
NPC1 O15118 3/20 0.51
NPSR1 Q6W5P4 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
LMNA P02545 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744280 0.98 KDM4E (0.66) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL6515761 0.96 KDM4E (0.64) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL6515756 0.96 KDM4E (0.64) KDM4EALDH1A1MAPTHPGDGAA
Hydrochloric Acid SCHEMBL6512620 0.96 KDM4E (0.64) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL24820015 0.84 KDM4E (0.61) KDM4EALDH1A1MAPTHPGDGAA
Hydrochloric Acid SCHEMBL6752001 0.82 KDM4E (0.59) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL5254193 0.81 LMNA (0.57) KDM4EALDH1A1MAPTGAAHSD17B10
SCHEMBL192100 0.81 KDM4E (0.72) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL29375113 0.81 KDM4E (0.72) KDM4EALDH1A1MAPTHPGDGAA
SCHEMBL21383063 0.81 CA1 (0.57) KDM4EALDH1A1MAPTHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed