Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274777 | 0.90 | MAP3K14 (0.44) | MAP3K14LMNAMAPTPKMALDH1A1 | |
| SCHEMBL29129779 | 0.88 | MAP3K14 (0.46) | MAP3K14LMNAMAPTPKMALDH1A1 | |
| Acrylic Acid SCHEMBL31065462 | 0.87 | ALDH1A1 (0.33) | HLCSMAP3K14LMNAMAPTPKM | |
| SCHEMBL1536267 | 0.84 | MAP3K14 (0.43) | MAP3K14LMNAMAPTPKML3MBTL1 | |
| SCHEMBL6536968 | 0.81 | ALDH1A1 (0.54) | HLCSMAP3K14LMNAMAPTPKM | |
| SCHEMBL3372427 | 0.81 | ALDH1A1 (0.54) | HLCSMAP3K14LMNAMAPTPKM | |
| SCHEMBL5617175 | 0.81 | ALDH1A1 (0.54) | HLCSMAP3K14LMNAMAPTPKM | |
| SCHEMBL734754 | 0.81 | ALDH1A1 (0.54) | HLCSMAP3K14LMNAMAPTPKM | |
| SCHEMBL8697031 | 0.81 | ALDH1A1 (0.54) | HLCSMAP3K14LMNAMAPTPKM | |
| SCHEMBL18626078 | 0.81 | ALDH1A1 (0.54) | HLCSMAP3K14LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354950-A | ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES | TEXACO INC. (US) | 1982-10-19 | — | — | US | claimed |
| EP-1481043-B1 | HYDROXY AROMATIC MANNICH BASE CONDENSATION PRODUCTS AND THE USE THEREOF AS SOOT DISPERSANTS IN LUBRICATING OIL COMPOSITIONS | INFINEUM INT LTD (GB) | 2017-11-29 | — | — | EP | disclosed |
| CN-100430369-C | Hydroxy aromatic mannich base condensation products and use thereof as soot dispersants in lubricating oil compsns. | INFINEUM INT LTD (GB) | 2008-11-05 | — | — | CN | disclosed |
| US-6855674-B2 | Hydroxy aromatic Mannich base condensation products and the use thereof as soot dispersants in lubricating oil compositions | INFINEUM INTERNATIONAL LTD. (GB) | 2005-02-15 | — | — | US | disclosed |
| EP-1481043-A2 | HYDROXY AROMATIC MANNICH BASE CONDENSATION PRODUCTS AND THE USE THEREOF AS SOOT DISPERSANTS IN LUBRICATING OIL COMPOSITIONS | Infineum International Ltd. (GB) | 2004-12-01 | — | — | EP | disclosed |
| CN-1541200-A | Hydroxy aromatic mannich base condensation products and use thereof as soot dispersants in lubricating oil compsns. | ŵ��ķ | 2004-10-27 | — | — | CN | disclosed |
| EP-1457548-A1 | Oxazines as such and as dispersants in lubricating compositions | Infineum International Limited (GB) | 2004-09-15 | — | — | EP | disclosed |
| CN-1472204-A | Condensed products of hydroxy aromatic mannich alkali and its use as ash disperser in lubricant composition | 英菲诺姆国际有限公司 | 2004-02-04 | — | — | CN | disclosed |
| US-20030173251-A1 | Hydroxy aromatic mannich base condensation products and the use thereof as soot dispersants in lubricating oil compositions | INFINEUM INTERNATIONAL LIMITED (GB) | 2003-09-18 | — | — | US | disclosed |
| US-6495496-B2 | CONDENSATES OF HYDROXY AROMATIC COMPOUNDS, AN ALDEHYDE AND AN AMINE | INFINEUM INTERNATIONAL LTD. (GB) | 2002-12-17 | — | — | US | disclosed |
| US-4913830-A | BORATED POLYMERS MADE FROM POLYLACTONE, AMINE, ALDEHYDE, PHENOL-MODIFIED POLYOLEFIN | EXXON CHEMICAL PATENTS INC. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0357215-A1 | Ethylene alpha-olefin mannich base viscosity index improver/dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0357217-A2 | Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0356010-A1 | Ethylene alpha-olefin polymer substituted Mannich base lubricant dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4828742-A | OIL AND FUEL ADDITIVES | EXXON CHEMICAL PATENTS, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4820432-A | FROM LACTONE, AMINE, ALDEHYDE, HYDROXYARYLAMINE, AND HYDROCARBYL SUBSTITUTED UNSATURATED DICARBOXYLIC ACID | EXXON CHEMICAL PATENTS INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0304175-A1 | Lactone-modified, Mannich base dispersant additives useful in oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0302643-A1 | Lactone-modified mannich base dispersant additives useful in oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4354950-A | ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES | TEXACO INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4354950-A | ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES | TEXACO INC. (US) | 1982-10-19 | — | — | US | disclosed |