Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376628 | 0.82 | MAPK14 (0.50) | MAOBMCHR1GSK3BBACE1MAPK14 | |
| SCHEMBL6526149 | 0.78 | MAOB (0.53) | MAOBGSK3BBACE1MAPK14 | |
| SCHEMBL4381779 | 0.76 | MAPK14 (0.65) | MAOBMCHR1MAPK14 | |
| SCHEMBL4382507 | 0.75 | MCHR1 (0.55) | MCHR1MAPK14 | |
| SCHEMBL4375944 | 0.73 | MAOB (0.53) | MAOBMCHR1MAPK14 | |
| SCHEMBL94520 | 0.71 | NSD2 (0.54) | MAOBMCHR1GSK3BBACE1IDO1 | |
| SCHEMBL4375940 | 0.71 | MCHR1 (0.53) | MAOBMCHR1 | |
| SCHEMBL4376955 | 0.71 | MAPK14 (0.56) | MAOBGSK3BBACE1MAPK14 | |
| SCHEMBL13450401 | 0.71 | MAOB (0.60) | MAOBGSK3BBACE1IDO1AGXT | |
| SCHEMBL4381266 | 0.69 | MAPK14 (0.65) | MAOBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |