Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 18/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376955 | 0.82 | MAPK14 (0.56) | MAOBMAPK14GSK3BBACE1 | |
| SCHEMBL4386822 | 0.82 | MAOB (0.48) | MAOBMAPK14GSK3BBACE1 | |
| SCHEMBL4381266 | 0.80 | MAPK14 (0.65) | MAOBMAPK14 | |
| SCHEMBL4384621 | 0.79 | MAOB (0.45) | MAOBMAPK14 | |
| SCHEMBL4381727 | 0.79 | MAPK14 (0.65) | MAOBMAPK14GSK3BBACE1 | |
| SCHEMBL4378569 | 0.79 | MAPK14 (0.53) | MAOBMAPK14 | |
| SCHEMBL6525480 | 0.78 | MAOB (0.49) | MAOBMAPK14GSK3BBACE1 | |
| SCHEMBL4374553 | 0.78 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL17809524 | 0.78 | MAPK14 (0.66) | MAOBMAPK14 | |
| SCHEMBL4465611 | 0.77 | MAOB (0.46) | MAOBMAPK14GSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |