Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530524 | 0.81 | KMT2A (0.41) | KMT2AMEN1BCL2L1ALDH1A1MAPT | |
| SCHEMBL6025517 | 0.81 | KMT2A (0.44) | KMT2AMEN1BCL2L1ALDH1A1MAPT | |
| SCHEMBL6026281 | 0.79 | KMT2A (0.42) | KMT2AMEN1BCL2L1ALDH1A1MAPT | |
| SCHEMBL1542077 | 0.79 | MAPT (0.58) | KMT2AMEN1BCL2L1BCL2ALDH1A1 | |
| SCHEMBL6531283 | 0.78 | KMT2A (0.41) | KMT2AMEN1BCL2L1ALDH1A1MAPT | |
| SCHEMBL5744699 | 0.75 | BCL2L1 (0.48) | KMT2AMEN1BCL2L1BCL2ALDH1A1 | |
| SCHEMBL6025521 | 0.75 | KMT2A (0.42) | KMT2AMEN1BCL2L1ALDH1A1MAPT | |
| SCHEMBL28873438 | 0.74 | BCL2L1 (0.69) | BCL2L1BCL2 | |
| SCHEMBL2474106 | 0.74 | BCL2L1 (0.69) | BCL2L1BCL2 | |
| SCHEMBL6533313 | 0.73 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |