Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026281 | 0.80 | KMT2A (0.42) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL6531283 | 0.76 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL6025517 | 0.75 | KMT2A (0.44) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL6530524 | 0.75 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL6525575 | 0.73 | KMT2A (0.47) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL1701615 | 0.71 | KMT2A (0.47) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL6820933 | 0.68 | ALDH1A1 (0.61) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL6533327 | 0.68 | MAPT (0.44) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL25169485 | 0.68 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL29889311 | 0.68 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |