SCHEMBL652558

SCHEMBL652558

Clc1c(Cl)c(Cl)c2c(c1Cl)Oc1ccccc1O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHR P35869 12/20 1.00
ALOX5 P09917 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
NTSR1 P30989 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901611 1.00 AHR (1.00) AHRALOX5MAOAMAOBNTSR1
SCHEMBL29617290 1.00 AHR (1.00) AHRALOX5MAOAMAOBNTSR1
SCHEMBL1078819 0.91 AHR (0.82) AHRALOX5MAOAMAOBNTSR1
Pentachlorophenol SCHEMBL6761630 0.89 AHR (0.78) AHRMAOAMAOBLMNATSHR
SCHEMBL5588066 0.82 AHR (0.70) AHRALOX5MAOAMAOBNTSR1
SCHEMBL5885513 0.79 AHR (1.00) AHRTSHR
SCHEMBL3172291 0.79 AHR (0.69) AHRLMNATSHR
SCHEMBL29488626 0.79 AHR (0.69) AHRLMNATSHR
SCHEMBL2886579 0.77 AHR (0.73) AHR
SCHEMBL2463391 0.75 AHR (0.59) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367321-A1 COMPOSITIONS AND METHODS INVOLVING ADGRG6 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-04 US claimed
WO-2023250130-A2 COMPOSITIONS AND METHODS INVOLVING ADGRG6 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-12-28 WO claimed
CN-115406990-B Method for detecting dioxin in chlorinated paraffin industrial products RESEARCH CENTER FOR ECO-ENVIRONMENTAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2023-09-26 CN claimed
CN-115406990-A Method for detecting dioxin in chlorinated paraffin industrial product 中国科学院生态环境研究中心 2022-11-29 CN claimed
CN-115337911-A Preparation method of dioxin molecularly imprinted material 中山火炬职业技术学院 2022-11-15 CN claimed
CN-114444973-A Food safety risk assessment program based on exposure characteristics, toxicity pathways and biomarkers and framework system construction method 复旦大学 2022-05-06 CN claimed
US-20210299094-A1 METHODS OF UPREGULATING TIPARP AS ANTICANCER STRATEGIES CORNELL UNIVERSITY 2021-09-30 US claimed
WO-2020023616-A1 METHODS OF UPREGULATING TIPARP AS ANTICANCER STRATEGIES CORNELL UNIVERSITY (US) 2020-01-30 WO claimed
US-20180125971-A1 Modulation of the Immune Response THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2018-05-10 US claimed
US-20180071376-A1 TOLEROGENIC NANOPARTICLES FOR TREATING DIABETES MELLITUS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2018-03-15 US claimed
EP-0561786-A1 BLEACHING CHEMICAL PULP USING CHLORINE/CHLORINE DIOXIDE THEN OZONE INTERNATIONAL PAPER COMPANY (US) 1993-09-29 EP claimed
WO-1992003609-A1 BLEACHING CHEMICAL PULP USING CHLORINE/CHLORINE DIOXIDE THEN OZONE INTERNATIONAL PAPER COMPANY (US) 1992-03-05 WO claimed
EP-0252521-B1 PROCESS FOR DECOMPOSING POLYHALOGENATED COMPOUNDS Hagenmaier, Hanspaul, Prof.Dr. (DE) 1991-10-09 EP claimed
US-4981650-A Method for treatment of dioxin-contaminated media NATIONAL SCIENCE FOUNDATION 1991-01-01 US claimed
EP-0258006-A2 Monoclonal antibodies reactive with chlorinated dibenzo-p-dioxins and method of preparing and using same WESTINGHOUSE ELECTRIC CORPORATION (US) 1988-03-02 EP claimed
WO-1988000483-A1 PROCESS FOR DECOMPOSING POLYHALOGENATED COMPOUNDS HAGENMAIER HANS PAUL (DE) 1988-01-28 WO claimed
EP-0252521-A1 Process for decomposing polyhalogenated compounds Hagenmaier, Hanspaul, Prof.Dr. (DE) 1988-01-13 EP claimed
EP-0251635-A2 Monoclonal antibodies and method for detecting dioxins and dibenzofurans THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1988-01-07 EP claimed
EP-0021294-B1 CHEMICAL DETOXIFICATION OF TOXIC CHLORINATED AROMATIC COMPOUNDS Vertac Chemical Corporation (US) 1984-10-10 EP claimed
EP-0027745-B1 A PROCESS FOR THE ELECTROCHEMICAL DEGRADATION OF PERSISTENT ORGANIC COMPOUNDS, WITH HARMFUL OR POTENTIALLY HARMFUL PROPERTIES CRECONSULT LIMITED (GB) 1984-08-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299094-A1 METHODS OF UPREGULATING TIPARP AS ANTICANCER STRATEGIES TIPARP, TEAD1, TEAD2 AHR 143/4885ALOX5 3621/4885MAOA 1725/4885
US-20180071376-A1 TOLEROGENIC NANOPARTICLES FOR TREATING DIABETES MELLITUS IAPP, NFATC1, CD4 AHR 2191/4885ALOX5 3504/4885MAOA 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.