SCHEMBL6525876

SCHEMBL6525876

CCCCCCCCCCSC1C=CC(SCCCCCCCCCC)C=C1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
THRB P10828 2/20 0.42
HSD17B10 Q99714 2/20 0.37
CES2 O00748 1/20 0.37
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
GMNN O75496 1/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
BLM P54132 1/20 0.37
CA2 P00918 1/20 0.35
DNM1 Q05193 6/20 0.35
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6525839 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL6522176 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL6521610 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL6521704 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL6520145 0.97 THRB (0.37) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL6527169 0.89 TSHR (0.33) TSHRTHRBLMNA
SCHEMBL4350774 0.84 THRB (0.33) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL4353053 0.84 THRB (0.33) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL4349186 0.84 THRB (0.33) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL4354959 0.84 THRB (0.33) TSHRTHRBHSD17B10CES2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487071-B2 Polyether polymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-16 US disclosed
US-20110065889-A1 POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed