Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.85 |
| ▸ | DRD3 | P35462 | 3/20 | 0.85 |
| ▸ | HTR1A | P08908 | 4/20 | 0.83 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.73 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.73 |
| ▸ | HTR7 | P34969 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 2/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414460 | 0.92 | DRD2 (1.00) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL30206503 | 0.92 | DRD2 (0.78) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL1255253 | 0.92 | DRD2 (0.78) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11651993 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Dimetholizine SCHEMBL2110772 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL2215388 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL7821310 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL7433412 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL1193323 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8980706 | 0.91 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021521-A1 | PREPARATION OF 1-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-3-(2,6-DIOXOPIPERIDIN-1-YL) PROPANE HYDROCHLORIDE | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | disclosed |