Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL1928156 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRTP53CYP2A6TRPA1 | |
| Benzene SCHEMBL28217033 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53CYP2A6TRPA1 | |
| Hydrogen Peroxide SCHEMBL11228536 | 0.80 | — | — | |
| Hydrogen Peroxide SCHEMBL11231632 | 0.80 | ALDH1A1 (0.71) | ALDH1A1TSHRTP53TRPA1LMNA | |
| SCHEMBL724735 | 0.79 | — | — | |
| SCHEMBL18285 | 0.79 | — | — | |
| Benzene SCHEMBL28113048 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53CYP2A6TRPA1 | |
| Benzene SCHEMBL29131459 | 0.75 | ALDH1A1 (0.73) | ALDH1A1TSHRCYP2A6TRPA1LMNA | |
| Water SCHEMBL1290581 | 0.72 | ALDH1A1 (0.83) | ALDH1A1TSHRTRPA1MAPK1 | |
| Water SCHEMBL620210 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859695-B | Synthesis method of 2-aryl-3- (4-hydroxy-2H-pyran-2-ketone-3-yl) indole derivative | 苏州大学 | 2019-02-26 | — | — | CN | claimed |
| CN-106008477-B | 3- (2-aryl-1H-indole-3-yl) -4-hydroxyfuran-2 (5H) -ketone and synthetic method thereof | 苏州大学 | 2019-02-26 | — | — | CN | claimed |
| CN-106008476-B | 3- (2-aryl-1H-indole-3-yl) -4-hydroxycoumarin derivative and synthetic method thereof | 苏州大学 | 2019-02-26 | — | — | CN | claimed |
| CN-108218869-A | A kind of pyrazolo [3,4-b] pyrrolo- [3,4-d] pyridine derivate and its synthetic method | 苏州大学 | 2018-06-29 | — | — | CN | claimed |
| CN-106008476-A | 3- (2-aryl-1H-indole-3-yl) -4-hydroxycoumarin derivative and synthetic method thereof | 苏州大学 | 2016-10-12 | — | — | CN | claimed |
| CN-106008477-A | 3- (2-aryl-1H-indole-3-yl) -4-hydroxyfuran-2 (5H) -ketone and synthetic method thereof | 苏州大学 | 2016-10-12 | — | — | CN | claimed |
| CN-105859695-A | 2-aryl-3- (4-hydroxy-2H-pyran-2-ketone-3-yl) indole derivative and synthetic method thereof | 苏州大学 | 2016-08-17 | — | — | CN | claimed |
| CN-103140208-A | Encapsulated compositions comprising aldehyde fragrance precursors | GIVAUDAN SA | 2013-06-05 | — | — | CN | claimed |
| CN-101448777-B | Fragrance precursor | KAO CORP SA | 2012-07-04 | — | — | CN | claimed |
| CN-101448777-A | Fragrance precursor | KAO CORP SA (ES) | 2009-06-03 | — | — | CN | claimed |
| CN-1466582-A | Substituted aryl ketones and their use as herbicides | 拜尔农作物科学股份公司 | 2004-01-07 | — | — | CN | claimed |
| CN-105859695-B | Synthesis method of 2-aryl-3- (4-hydroxy-2H-pyran-2-ketone-3-yl) indole derivative | 苏州大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-106008477-B | 3- (2-aryl-1H-indole-3-yl) -4-hydroxyfuran-2 (5H) -ketone and synthetic method thereof | 苏州大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-106008476-B | 3- (2-aryl-1H-indole-3-yl) -4-hydroxycoumarin derivative and synthetic method thereof | 苏州大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-103781892-B | Improvements relating to polymers, deposition aids, targeted benefit agents and matrix treatment compositions | 荷兰联合利华有限公司 | 2018-08-07 | — | — | CN | disclosed |
| CN-102695786-A | Laundry compositions | UNILEVER PLC | 2012-09-26 | — | — | CN | disclosed |
| CN-101448777-B | Fragrance precursor | KAO CORP SA | 2012-07-04 | — | — | CN | disclosed |
| CN-101448777-A | Fragrance precursor | KAO CORP SA (ES) | 2009-06-03 | — | — | CN | disclosed |
| WO-2005113023-A1 | USE OF ARGININE AND LIKE SUBSTANCES AND METHYLGLYOXAL AND LIKE SUBSTANCES IN DIALYSIS MACHINES | HAIK JR GEORGE M (US) | 2005-12-01 | — | — | WO | disclosed |
| CN-1466582-A | Substituted aryl ketones and their use as herbicides | 拜尔农作物科学股份公司 | 2004-01-07 | — | — | CN | disclosed |