SCHEMBL652710

SCHEMBL652710

COc1ccc2ccccc2c1C#[N+][O-]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
NQO1 P15559 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
NISCH Q9Y2I1 1/20 0.39
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
IMPDH2 P12268 1/20 0.38
IMPDH1 P20839 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
FGB P02675 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12290140 0.82 MAPT (0.36) MAPTKDM4EHPGDALDH1A1RAB9A
SCHEMBL10019292 0.77 CYP1A2 (0.48) MAPTKDM4EHPGDMEN1KMT2A
SCHEMBL881195 0.77 MAPT (0.58) MAPTNQO1KDM4EHPGDMEN1
SCHEMBL12988355 0.77 MAPT (0.58) MAPTNQO1KDM4EHPGDMEN1
SCHEMBL3081463 0.77 MAPT (0.58) MAPTNQO1KDM4EHPGDMEN1
SCHEMBL2789098 0.77 MAPT (0.58) MAPTNQO1KDM4EHPGDMEN1
SCHEMBL2429770 0.76 CA1 (0.44) MAPTKDM4EHPGDALDH1A1RAB9A
SCHEMBL12267869 0.76 MAPT (0.56) MAPTNQO1KDM4EHPGDMEN1
SCHEMBL10019289 0.75 RIPK1 (0.37)
SCHEMBL26259291 0.73 MAPT (0.53) MAPTNQO1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969480-B2 Polymer alloy and rubber product, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2015-03-03 US disclosed
US-8969480-B2 Polymer alloy and rubber product, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2015-03-03 US disclosed
US-8969480-B2 Polymer alloy and rubber product, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2015-03-03 US disclosed
US-20140018503-A1 POLYMER ALLOY AND RUBBER PRODUCT, AND PRODUCTION METHOD THEREOF TOYODA GOSEI CO., LTD. (JP) 2014-01-16 US disclosed
US-20140018503-A1 POLYMER ALLOY AND RUBBER PRODUCT, AND PRODUCTION METHOD THEREOF TOYODA GOSEI CO., LTD. (JP) 2014-01-16 US disclosed
US-20140018503-A1 POLYMER ALLOY AND RUBBER PRODUCT, AND PRODUCTION METHOD THEREOF TOYODA GOSEI CO., LTD. (JP) 2014-01-16 US disclosed
US-8507610-B2 Modified polymer material modified by nitrile oxide, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2013-08-13 US disclosed
US-8507610-B2 Modified polymer material modified by nitrile oxide, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2013-08-13 US disclosed
US-8507611-B2 Crosslinkable polymer material, crosslinked polymer material, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2013-08-13 US disclosed
WO-2012114591-A1 POLYMER ALLOY, RUBBER PRODUCT, AND METHOD FOR PRODUCING POLYMER ALLOY AND RUBBER PRODUCT 豊田合成株式会社 (JP) 2012-08-30 WO disclosed
US-20120046418-A1 CROSSLINKABLE POLYMER MATERIAL, CROSSLINKED POLYMER MATERIAL, AND PRODUCTION METHOD THEREOF TOKYO INSTITUTE OF TECHNOLOGY (JP) 2012-02-23 US disclosed
US-20110054134-A1 Modified polymer material modified by nitrile oxide, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2011-03-03 US disclosed
US-20110054134-A1 Modified polymer material modified by nitrile oxide, and production method thereof TOYODA GOSEI CO., LTD. (JP) 2011-03-03 US disclosed