SCHEMBL315396

SCHEMBL315396

NC1=Nc2cccc3cccc(c23)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 11/20 0.62
MAPT P10636 9/20 0.62
MCL1 Q07820 3/20 0.62
KMT2A Q03164 11/20 0.61
LMNA P02545 5/20 0.61
USP2 O75604 2/20 0.61
ALOX12 P18054 1/20 0.61
MEN1 O00255 10/20 0.58
KDM4E B2RXH2 3/20 0.57
APAF1 O14727 1/20 0.57
PLCG1 P19174 1/20 0.57
CCR6 P51684 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
NPC1 O15118 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2D6 P10635 2/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL9555445 0.98 GAA (0.61) GAAMAPTMCL1KMT2ALMNA
Hydrochloric Acid SCHEMBL8649799 0.98 GAA (0.61) GAAMAPTMCL1KMT2ALMNA
Methylglyoxal SCHEMBL6013425 0.85 GAA (0.51) GAAMAPTMCL1KMT2ALMNA
SCHEMBL15018298 0.80 KMT2A (0.77) GAAMAPTMCL1KMT2ALMNA
SCHEMBL6527367 0.78 GAA (0.65) GAAMAPTMCL1KMT2ALMNA
SCHEMBL15040701 0.77 GAA (0.62) GAAMAPTMCL1KMT2ALMNA
SCHEMBL1268566 0.77 GAA (0.62) GAAMAPTMCL1KMT2ALMNA
SCHEMBL8485540 0.77 GAA (1.00) GAAMAPTMCL1KMT2ALMNA
SCHEMBL4197315 0.77 GAA (0.62) GAAMAPTMCL1KMT2ALMNA
SCHEMBL1773293 0.77 GAA (0.62) GAAMAPTMCL1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3899034-B1 METHODS FOR RNA ANALYSIS CureVac SE (DE) 2026-03-18 EP claimed
US-12029716-B2 Derivatives of korormicin useful as antibiotics Viotika Life Sciences (CA) 2024-07-09 US claimed
WO-2024120884-A1 AROMATIC AMINE MODIFIED ACID-OLEFIN COPOLYMER FOR LUBRICANTS BASF SE (DE) 2024-06-13 WO claimed
US-20220257555-A1 DERIVATIVES OF KORORMICIN USEFUL AS ANTIBIOTICS Viotika Life Sciences Inc. (CA) 2022-08-18 US claimed
US-20220073962-A1 METHODS FOR RNA ANALYSIS CUREVAC AG (DE) 2022-03-10 US claimed
EP-3899034-A1 METHODS FOR RNA ANALYSIS CureVac AG (DE) 2021-10-27 EP claimed
EP-3555246-B1 MULTI-FUNCTIONAL OLEFIN COPOLYMERS AND LUBRICATING COMPOSITIONS CONTAINING SAME AFTON CHEMICAL CORP (US) 2020-11-25 EP claimed
WO-2020127959-A1 METHODS FOR RNA ANALYSIS CUREVAC AG (DE) 2020-06-25 WO claimed
EP-3405554-B1 LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND CHEVRON ORONITE CO (US) 2019-12-25 EP claimed
EP-3555246-A1 MULTI-FUNCTIONAL OLEFIN COPOLYMERS AND LUBRICATING COMPOSITIONS CONTAINING SAME Afton Chemical Corporation (US) 2019-10-23 EP claimed
EP-0465031-A1 Multifunctional viscosity index improvers TEXACO DEVELOPMENT CORPORATION (US) 1992-01-08 EP claimed
US-5075383-A Graft and amine derivatized copolymer of ethyleneand alpha olefin TEXACO INC. (US) 1991-12-24 US claimed
US-5013469-A Butylene-ethylene-styrene polymer reacted with maleic anhydride and aromatic polyamine TEXACO INC. (US) 1991-05-07 US claimed
US-5013468-A Terpolymer of aminoalkyl acrylamide or acrylate, an acrylamide and an acrylate TEXACO INC. (US) 1991-05-07 US claimed
US-5013470-A Antioxidant VII lubricant additive TEXACO INC. (US) 1991-05-07 US claimed
EP-0414343-A1 VI improver, dispersant, and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1991-02-27 EP claimed
EP-0396297-A2 Dispersant - anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1990-11-07 EP claimed
EP-0338672-A1 Viscosity index improver, dispersant and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1989-10-25 EP claimed
US-4863623-A VISCOSITY INDEX, GRAFT POLYMERS OF ETHYLENE MODIFIED WITH AMINE COMPOUND TEXACO INC. (US) 1989-09-05 US claimed
EP-0170414-A2 Process for treating metal surface Hitachi Chemical Co., Ltd. (JP) 1986-02-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220257555-A1 DERIVATIVES OF KORORMICIN USEFUL AS ANTIBIOTICS HRH3, HRH1, OPRK1 GAA 3521/4885MAPT 4535/4885MCL1 4399/4885
US-12029716-B2 Derivatives of korormicin useful as antibiotics HRH3, HRH1, OPRK1 GAA 3521/4885MAPT 4535/4885MCL1 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.