Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906559 | 0.87 | ADORA3 (0.47) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL2671274 | 0.79 | ADORA3 (0.45) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL2671447 | 0.78 | ADORA3 (0.44) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL23114151 | 0.75 | ADORA3 (0.48) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL5906629 | 0.72 | NPC1 (0.44) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL2671418 | 0.70 | ADORA3 (0.42) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL5906720 | 0.70 | SSTR5 (0.35) | ADORA3NPC1ALDH1A1GABRA2GABRB2 | |
| SCHEMBL126072 | 0.69 | — | — | |
| SCHEMBL3676305 | 0.69 | ADORA2A (0.54) | ADORA3ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL5906668 | 0.68 | TSHR (0.43) | ADORA3ALDH1A1NPSR1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040152-A1 | HETEROYCLYLPHENYL-AND HETEROCYCLYLPYRIDYL-SUBSTITUTED AZOLECARBOXAMIDES AS HERBICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |
| WO-2004106324-A1 | AZOLECARBOXAMIDE HERBICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |