SCHEMBL6528107

SCHEMBL6528107

CC(C)(C)NC(=O)C1(C2CCCCC2)CCN(C(=O)OC(C)(C)C)CC1.CC(C)(C)NC(=O)C1(C2CCCCC2)CCNCC1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MC4R P32245 17/20 0.51
MC5R P33032 16/20 0.51
EPHX1 P07099 1/20 0.44
MC3R P41968 10/20 0.44
MC1R Q01726 9/20 0.44
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324396 0.93 EPHX1 (0.50) MC4RMC5REPHX1MC3RMC1R
SCHEMBL1325197 0.84 MC4R (0.42) MC4RMC5REPHX1MC3RMC1R
SCHEMBL6507349 0.78 EPHX1 (0.52) MC4RMC5REPHX1HPGD
SCHEMBL4609802 0.78 EPHX1 (0.51) EPHX1HPGD
SCHEMBL6513102 0.77 EPHX1 (0.46) MC4RMC5REPHX1HPGD
SCHEMBL23439148 0.77 EPHX1 (0.50) EPHX1HPGD
SCHEMBL396843 0.77 EPHX1 (0.49) EPHX1HPGD
SCHEMBL23783193 0.76 HPGD (0.43) EPHX1HPGD
SCHEMBL13677292 0.75 MC4R (0.46) MC4RMC5RMC3RMC1R
SCHEMBL3254458 0.75 EPHX1 (0.54) EPHX1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005047253-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO disclosed