Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.46 |
| ▸ | MC5R | P33032 | 19/20 | 0.46 |
| ▸ | MC3R | P41968 | 16/20 | 0.46 |
| ▸ | MC1R | Q01726 | 12/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14111012 | 0.87 | MC4R (0.45) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL13676985 | 0.84 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL1324396 | 0.81 | EPHX1 (0.50) | MC4RMC5RMC3RMC1R | |
| SCHEMBL1325197 | 0.80 | MC4R (0.42) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13677284 | 0.80 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL1324395 | 0.76 | MC4R (0.40) | MC4RMC5RMC3RMC1R | |
| SCHEMBL6528107 | 0.75 | MC4R (0.51) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14585906 | 0.74 | MC4R (0.51) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14585908 | 0.73 | MC4R (0.53) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13270912 | 0.73 | MC4R (0.37) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334290-B2 | CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2012-12-18 | — | — | US | disclosed |
| US-20090264405-A1 | Cetp Inhibitors | MERCK SHARP & DOHME LLC | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264405-A1 | Cetp Inhibitors | CETP, APOB, PCSK9 | MC4R 2976/4885MC5R 3921/4885MC3R 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.