⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787875 | 0.64 | TDP1 (0.36) | — | |
| SCHEMBL766307 | 0.58 | — | — | |
| SCHEMBL3678505 | 0.58 | — | — | |
| SCHEMBL28915337 | 0.58 | — | — | |
| 1,1,2,2-Tetrachloroethane SCHEMBL2564 | 0.52 | — | — | |
| 1,1,2,2-Tetrachloroethane SCHEMBL8872399 | 0.52 | TDP1 (1.00) | — | |
| Chloroform SCHEMBL4258459 | 0.51 | — | — | |
| SCHEMBL11812657 | 0.51 | — | — | |
| SCHEMBL25404221 | 0.50 | — | — | |
| SCHEMBL19133 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537094-A2 | METHODS AND COMPOSITIONS FOR CONVERTING TAXANE AMIDES TO PACLITAXEL OR OTHER TAXANES | Natural Pharmaceuticals, Inc. (US) | 2005-06-08 | — | — | EP | claimed |
| WO-2004013096-A2 | METHODS AND COMPOSITIONS FOR CONVERTING TAXANE AMIDES TO PACLITAXEL OR OTHER TAXANES | NATURAL PHARMACEUTICALS INC. (US) | 2004-02-12 | — | — | WO | claimed |
| US-5142039-A | β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1992-08-25 | — | — | US | claimed |
| EP-0000800-B1 | SELECTIVE N-PROTECTION OF AMINOGLYCOSIDES AND NOVEL, SELECTIVELY PROTECTED AMINOGLYCOSIDE INTERMEDIATES | Technobiotic Ltd. (CH) | 1980-12-10 | — | — | EP | claimed |
| US-4066752-A | 1-Desamino-1-hydroxy and 1-desamino-1-epi-hydroxy-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols; 1-desamino-1-oxo-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols, intermediates and use as antibacterial agents | SCHERING CORPORATION (US) | 1978-01-03 | — | — | US | claimed |
| EP-1289998-A1 | NEW PROCESS FOR THE PREPARATION OF VINYL-PYRROLIDINONE CEPHALOSPORINE DERIVATIVES | Basilea Pharmaceutica AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090111-A1 | NEW PROCESS FOR THE PREPARATION OF VINYL-PYRROLIDINONE CEPHALOSPORINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2001-11-29 | — | — | WO | disclosed |
| US-5462952-A | Have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| US-5066668-A | Enzyme inhibitors, cyclooxygenase and lipoxygenase, mixture with nonsteroid antiinflammatory agent | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0401857-A2 | Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4962119-A | Inhibit lipoxygenase, cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1990-10-09 | — | — | US | disclosed |