SCHEMBL787875

SCHEMBL787875

ClC(Cl)C(Cl)OC(Cl)C(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628406 0.73 TDP1 (0.31) TDP1
SCHEMBL28915337 0.64
SCHEMBL766307 0.64
SCHEMBL3678505 0.64
SCHEMBL6528145 0.64
SCHEMBL28857261 0.64 ALDH1A1 (0.39)
SCHEMBL5688490 0.64 ALDH1A1 (0.39)
Hydrochloric Acid SCHEMBL11468853 0.61
SCHEMBL18423818 0.61
1,1,2,2-Tetrachloroethane SCHEMBL2564 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104530417-B A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2017-09-08 CN claimed
CN-104530415-B A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance 厦门赛诺邦格生物科技股份有限公司 2017-09-01 CN claimed
US-20250215037-A1 ELECTROCHEMICALLY-CLEAVABLE LINKERS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-07-03 US disclosed
US-20250215037-A1 ELECTROCHEMICALLY-CLEAVABLE LINKERS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-07-03 US disclosed
US-12281134-B2 Electrochemically-cleavable linkers MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-04-22 US disclosed
US-12281134-B2 Electrochemically-cleavable linkers MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-04-22 US disclosed
US-20250115635-A1 LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-04-10 US disclosed
US-20250115635-A1 LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-04-10 US disclosed
US-12215121-B2 Linker structures with minimal scar for enzymatic synthesis MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-02-04 US disclosed
US-12215121-B2 Linker structures with minimal scar for enzymatic synthesis MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-02-04 US disclosed
EP-4355874-A1 METHODS OF PREPARING BIVALENT MOLECULES Insitro, Inc. (US) 2024-04-24 EP disclosed
US-20030224409-A1 Method for producing and screening mass-coded combinatorial libraries for drug discovery and target validation NEOGENESIS, INC., A DELAWARE CORPORATION 2003-12-04 US disclosed
US-20030138788-A1 Method for producing and screening mass-coded combinatorial libraries for drug discovery and target validation NEOGENESIS PHARMACEUTICALS, INC. (US) 2003-07-24 US disclosed
US-20020182714-A1 Method for producing and screening mass-coded combinatorial libraries for drug discovery and target validation NEOGENESIS PHARMACEUTICALS, INC. (US) 2002-12-05 US disclosed
US-20020172970-A1 Method for producing and screening mass-coded combinatorial libraries for drug discovery and target validation NEOGENESIS PHARMACEUTICALS, INC. (US) 2002-11-21 US disclosed
WO-2002018540-A2 PYRIDINE DERIVATIVES USEFUL AS CD40:CD154 BINDING INTERRUPTOR COMPOUNDS AND USE THEREOF TO TREAT IMMUNOLOGICAL COMPLICATIONS BIOGEN, INC. (US) 2002-03-07 WO disclosed
US-6207861-B1 Method for producing and screening mass coded combinatorial libraries for drug discovery and target validation NEOGENESIS, INC. 2001-03-27 US disclosed
EP-1045819-A1 METHOD FOR PRODUCING MASS-CODED COMBINATORIAL LIBRARIES Neogenesis, Inc. (US) 2000-10-25 EP disclosed
WO-1999035109-A1 METHOD FOR PRODUCING MASS-CODED COMBINATORIAL LIBRARIES NEOGENESIS, INC. (US) 1999-07-15 WO disclosed
US-4508658-A Pentahalophenyl ester of cyanoacetic acid derivatives CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1985-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115635-A1 LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS RNGTT, MMP1, UNG TDP1 385/4885
US-20250215037-A1 ELECTROCHEMICALLY-CLEAVABLE LINKERS RNGTT, DNPEP, DTYMK TDP1 165/4885
US-12281134-B2 Electrochemically-cleavable linkers RNGTT, DNPEP, DTYMK TDP1 165/4885
US-20030224409-A1 Method for producing and screening mass-coded combinatorial libraries for drug discovery and target validation TPX2, LPXN, PDHX TDP1 3967/4885
US-12215121-B2 Linker structures with minimal scar for enzymatic synthesis RNGTT, MMP1, UNG TDP1 385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.