Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951436 | 0.86 | TDP1 (0.57) | MAPK1TDP1TSHRNOTUMCHUK | |
| SCHEMBL835436 | 0.83 | MAPK1 (0.52) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| SCHEMBL6980080 | 0.83 | MAPT (0.57) | MAPK1TDP1TSHRNOTUML3MBTL1 | |
| SCHEMBL11638729 | 0.82 | MAPK1 (0.61) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| SCHEMBL26416251 | 0.82 | MAPK1 (0.70) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| SCHEMBL7979628 | 0.82 | MAPK1 (0.57) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| SCHEMBL92379 | 0.82 | MAPK1 (0.57) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| SCHEMBL11553918 | 0.81 | MAPK1 (0.54) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| SCHEMBL3105661 | 0.81 | MAPK1 (0.50) | MAPK1TDP1TSHRCHUKTXNRD1 | |
| Hydrochloric Acid SCHEMBL12478354 | 0.81 | MAPK1 (0.56) | MAPK1TDP1TSHRCHUKTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |