Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913578 | 0.76 | RAB9A (0.47) | PARP1PDPK1ALDH1A1RAB9ALMNA | |
| SCHEMBL27496307 | 0.76 | CHEK1 (0.41) | PARP1PDPK1ALDH1A1RAB9ALMNA | |
| SCHEMBL269563 | 0.70 | — | — | |
| SCHEMBL120158 | 0.70 | — | — | |
| SCHEMBL17897153 | 0.68 | PDPK1 (0.40) | PARP1PDPK1ALDH1A1RAB9ALMNA | |
| SCHEMBL2284623 | 0.68 | PARP1 (0.43) | PARP1PDPK1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL3863547 | 0.68 | CYP1A2 (0.45) | PARP1PDPK1ALDH1A1RAB9ALMNA | |
| SCHEMBL914620 | 0.67 | CHEK1 (0.44) | ALDH1A1RAB9ALMNASMN1; SMN2KMT2A | |
| SCHEMBL16815323 | 0.67 | CYP1A2 (0.60) | PARP1PDPK1ALDH1A1RAB9ALMNA | |
| SCHEMBL383127 | 0.67 | KMT2A (0.44) | PARP1PDPK1ALDH1A1LMNATNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| WO-2017100593-A1 | THIENOPYRIMIDINONE NMDA RECEPTOR MODULATORS AND USES THEREOF | LUC THERAPEUTICS (US) | 2017-06-15 | — | — | WO | claimed |
| US-9445599-B2 | Lignin-based microparticles for the controlled release of agricultural actives | MONSANTO TECHNOLOGY LLC (US) | 2016-09-20 | — | — | US | claimed |
| CN-105017277-A | 2-substituted tetrahydrobenzo thieno pyrimidyl ketone derivative and preparation method and application thereof | UNIV WENZHOU MEDICAL | 2015-11-04 | — | — | CN | claimed |
| EP-2854534-A1 | COMPOSITIIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE | Bayer Cropscience AG (DE) | 2015-04-08 | — | — | EP | claimed |
| WO-2013178661-A1 | COMPOSITIIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2013-12-05 | — | — | WO | claimed |
| US-8324227-B2 | Thieno[2,3-D]-pyrimidin-4(3H)-one compounds with antifungal properties and process thereof | FDC LIMITED (US) | 2012-12-04 | — | — | US | claimed |
| CN-1922171-B | Pyrimidine derivative | ASKA PHARM CO LTD | 2012-10-17 | — | — | CN | claimed |
| EP-2257555-B1 | THIENO[2,3-D]-PYRIMIDINE-4(3H)-ONE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND PROCESS THEREOF | NAT CHEMICAL LAB (IN) | 2012-07-04 | — | — | EP | claimed |
| WO-2003005816-A1 | LIGNIN MICROPARTICLES FOR CONTROLLED RELEASE OF AGRICULTURAL ACTIVES | MONSANTO TECHNOLOGY, LLC (US) | 2003-01-23 | — | — | WO | claimed |
| US-20030013612-A1 | Lignin-based microparticles for the controlled release of agricultural actives | MONSANTO TECHNOLOGY, L.L.C. (US) | 2003-01-16 | — | — | US | claimed |
| US-6432965-B1 | SYNERGISTIC MIXTURE | SYNGENTA CROP PROTECTION, INC. | 2002-08-13 | — | — | US | claimed |
| US-20020035038-A1 | Fungicidal combinations comprising thieno[2,3-d]pyrimidin-4-one | WALTER HARALD (CH) | 2002-03-21 | — | — | US | claimed |
| US-6323208-B1 | COMPOUNDS TO TREAT NEURODEGENERATIVE, PSYCHOTROPIC DRUG AND ALCOHOL INDUCED CENTRAL AND INDUCED CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS. | PFIZER INC | 2001-11-27 | — | — | US | claimed |
| EP-1124422-A1 | FUNGICIDAL COMBINATIONS COMPRISING THIENO[2,3-d]PYRIMIDIN-4-ONE | Syngenta Participations AG (CH) | 2001-08-22 | — | — | EP | claimed |
| EP-1035773-A1 | FUNGICIDAL COMBINATIONS COMPRISING THIENO 2,3-d]PYRIMIDIN-4-ONE | Novartis AG (CH) | 2000-09-20 | — | — | EP | claimed |
| WO-2000027200-A1 | FUNGICIDAL COMBINATIONS COMPRISING THIENO[2,3-d]PYRIMIDIN-4-ONE | SYNGENTA PARTICIPATIONS AG (CH) | 2000-05-18 | — | — | WO | claimed |
| WO-1999027790-A1 | FUNGICIDAL COMBINATIONS COMPRISING THIENO[2,3-d]PYRIMIDIN-4-ONE | NOVARTIS AG (CH) | 1999-06-10 | — | — | WO | claimed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035038-A1 | Fungicidal combinations comprising thieno[2,3-d]pyrimidin-4-one | MANBA, TPMT, TH | PARP1 3222/4885PDPK1 4001/4885ALDH1A1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.